AIDS DOI: 10.1097/QAD.0000000000001572 Tenofovir-Induced Toxicity in Renal Proximal Tubular Epithelial Cells: Involvement of Mitochondria Lara Milián 1,2 , José E. Peris 3 , Patricia Gandía 3 , Isabel Andújar 1,2 # , Luis Pallardó 5 , Jose L. Górriz 5 *, and Ana Blas-García 1,2,4 * 1 Departament of Pharmacology, Faculty of Medicine, University of Valencia, Valencia, Spain 2 FISABIO, Valencia, Spain 3 Departament of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Valencia, Valencia, Spain 4 CIBERehd, Valencia, Spain 5 Servicio de Nefrología, Hospital Universitario Dr. Peset, Valencia, Spain * These authors contributed equally to the work Current address for Lara Milián: Departament of Pathology, Faculty of Medicine, University of Valencia, Valencia, Spain # Corresponding author: Isabel Andújar, Ph.D. E-mail: isabel.andujar@uv.es Address: Departament of Pharmacology, Faculty of Medicine and Dentistry, University of Valencia, Avda. Blasco Ibáñez 15-17, 46010 Valencia, Spain Tel: (+34) 963864624; Fax: (+34) 963983879 Running title: Tenofovir-induced mitochondrial toxicity Copyright © 2017 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.