Journal Pre-proof Photosynthesis of hypericin in aqueous medium: A greener approach to prodrug strategy design in photodynamic therapy Paulo Cesar de Souza Pereira, Renato Sonchini Gonçalves, Mariana Alves Zampar, Maiara C. Montanha, Flavia A. de Morais, Elza Kimura, Celso V. Nakamura, Marcos L. Bruschi, Noboru Hioka, Wilker Caetano PII: S0167-7322(19)34150-9 DOI: https://doi.org/10.1016/j.molliq.2020.112746 Reference: MOLLIQ 112746 To appear in: Journal of Molecular Liquids Received date: 24 July 2019 Revised date: 17 February 2020 Accepted date: 19 February 2020 Please cite this article as: P.C. de Souza Pereira, R.S. Gonçalves, M.A. Zampar, et al., Photosynthesis of hypericin in aqueous medium: A greener approach to prodrug strategy design in photodynamic therapy, Journal of Molecular Liquids(2020), https://doi.org/ 10.1016/j.molliq.2020.112746 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Published by Elsevier.