Journal of Nutrition & Food Sciences Research Article 1 J Nutr Food Sci, Vol. 10 Iss. 1 No: 768 OPEN ACCESS Freely available online J o u r n a l o f N u t r it i o n & F o o d S c i e n c e s ISSN: 2155-9600 Diet Oriented Safety of Pakistani Biryani with reference to Glycemic Response in Healthy Human Subjects Asif Ahmed 1 , Shaikh Nadeem Ahmed 1 , Sara Sadiq 2 , Lubna Farooq 1 *, Humaira Arif 1 , Sumreen Mujahid 1 1 Baqai Medical University, Karachi, Pakistan; 2 CMH Institute of Medical sciences, Bahawalpur, Pakistan ABSTRACT Introduction: Traditional Pakistani Biryani is popular food particularly among Asian population. The objective of this study was to evaluate glycemic response of compound test food in conjunction with Food Oriented Diet Safety in healthy human subjects. Material and methods: This Quasi-Interventional Study was conducted in research unit of Baqai medical university. This study was conducted in period of two days and twenty healthy volunteers were enrolled. On day 1; fasting blood sugars were checked. Subsequently on day 2 participants were instructed to report with 12 hr. fasting, Later Compound test food was offered according to Health Body Mass Index (BMI) and Calories Calculator. Sequential plasma glycemic response was recorded on 0, 30, 60, 90 and 120 minutes. Results: Day 1, Glycemic response of study subjects showed mean glycemic value of 104 mg/dl. Day 2, glycemic response of 0, 30, 60, 90 and 120 minutes showed of 118,130, 121,109, 106 mg/dl respectively. This study highlights desirable incremental and decremented glycemic response after 30 & 120 mins respectively. Conclusion: This study concludes; that consumption of tested compound food according to BMI expected to have physiological mean peak glycemic response. Therefore this study identifies that consumption of beef biryani is safe; as study population never showed abnormal mean glycemic peak. Keywords: Glycemic response and index; Food safety; Fasting blood sugar; Acceptable glycemic dynamics INTRODUCTION Traditional Pakistani Biryani (Mixture of Rice & Beef) is a high ranked compound food, rich in carbohydrate and protein; known for high nutritional and taste value. Human corpus is highly dependent on carbohydrate and protein metabolism [1]. Food that have high in carbohydrates as well as raised glycemic index (GI) is directly linked with metabolic, vascular and malignant derangements [2,3]. Carbohydrate (CHO) digestion gets complex after the addition of other nutrients such as protein, yogurt and vegetable etc. thus causes undesirable effects on GI value [1,4]. These changes may be because of change in CHO hydrolysis rate and delaying Gastric emptying time etc. Many dietary trials clearly indicate that food with Low Glycemic Index have more desirable health responses [5]. Previous researches indicates that consumption of rice lowers cholesterol levels, reducing blood pressure, preventing colorectal cancer& Cardiovascular diseases [6,7]. It’s hypothesized that consumption of combination of rice & beef (Biryani) would be beneficial for health. The aim of this research was to estimate glycemic burden of blood plasma glucose value in healthy volunteer after ingestion of compound test meal that contain rice, meat, yogurt, spices etc. MATERIAL AND METHODS A total of 30 subjects were enrolled and 10 were excluded from the study. Twenty healthy volunteers’ male (55%) and females (45%) with mean age of 32.7 were recruited from Baqai Medical University. Inclusion criteria All study subjects were recruited after the announcement of study and were enrolled consecutively as they appeared for enrollment. Exclusion criteria All smokers, Diabetes Mellitus and pregnant ladies who were taken any medicine were excluded from the study. Written informed consent was taken from all subjects. Study protocol This study was conducted over the period of two days. On day 1 st , all subjects were requested to observe with 12 hr fasting and requested to have Correspondence to: Lubna Farooq, Assistant Professor, Baqai Medical University, Karachi, Pakistan, Tel: +03332303941; E-mail: Jlubna85@gmail.com Received: November 19, 2019, Accepted: January 23, 2020, Published: January 30, 2020 Citation: Ahmed A, Ahmed SN, Sadiq S, Farooq L, Arif H, Mujahid S (2020) Diet Oriented Safety of Pakistani Biryani with reference to Glycemic Response in Healthy Human Subjects. J Nutr Food Sci 10:768. doi: 10.35248/2155-9600.20.10.768 Copyright: © 2020 Ahmed A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.