Sridevi G and Akifa Begum, Int. J. Res. Pharm. Sci., 2020, 11 (SPL3), 686-693 ORIGINAL ARTICLE INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES Published by JK Welfare & Pharmascope Foundation Journal Home Page: www.pharmascope.org/ijrps Inৎluence of circadian rhythm on individual differences in morningness-eveningness scale among normal healthy subjects Akifa Begum, Sridevi G * Department of Physiology, Saveetha dental college, Saveetha institute of Medical and Technical Sciences, Saveetha University, Chennai-600077, Tamil Nadu, India Article History: Received on: 23 Jul 2020 Revised on: 29 Aug 2020 Accepted on: 14 Sep 2020 Keywords: Circadian rhythm, morningness- eveningness scale, health ABSTRACT The circadian rhythm is a biological rhythm that produces physical, psy- chological and behavioural changes in a living organism, and it follows a daily cycle. This cycle depends on the response of the organism to light and darkness in the environment. The aim of the study was to analyse and evaluate the inϑluence of circadian rhythm on individual differences in morningness-eveningness attitude among the normal healthy subjects. Morn- ingness eveningness questionnaire is a standard tool to assess sleep, wakeful- ness alertness, self-awareness and best time activity of the individual either in the morning time or evening time. This questionnaire was self-administered, and it consisted of 10 questions and was circulated via google forms. The results revealed that a majority of 85% of the participants are evening types of persons and the signiϑicance level was a p-value < 0.05 of the chi-square test. The present study assessed the inϑluence of the circadian rhythm on the morningness-eveningness scale, and results revealed that most of the partic- ipants were alarm dependant, had difϑiculty in waking up. They were very active in the evening and went to bed very late. So, the study concluded that the majority of participants were evening type of person. * Corresponding Author Name: Sridevi G Phone: +91 9840325676 Email: sridevig.sdc@saveetha.com ISSN: 0975-7538 DOI: https://doi.org/10.26452/ijrps.v11iSPL3.3003 Production and Hosted by Pharmascope.org © 2020 | All rights reserved. INTRODUCTION Circadian rhythm or system is the natural internal process that regulates the sleep-wake pattern. The main cue inϑluencing the circadian system is the daylight. Neutral factors within mammals, headed by the suprachiasmatic nucleus of the hypothala- mus (Farhud and Aryan, 2018). Many of the ϑind- ings have led to the budding ϑield of chronotherapy, in which the doctors time medicine to the natural body rhythm (Fuller et al., 2006). There are a variety of predisposing factors consisting like geographical events, lifestyle changes and biological molecules in the organism that have an impact on the circadian rhythms (Dijk and Archer, 2009). The uncertain sleep-wake timing and disruption of the circadian rhythm, having unregulated sched- ules have led to increasing the incidence of chronic diseases. Circadian rhythm can affect the bodily functions like body temperature, sleep-wake cycle, blood counts, eating habits and digestion, hormone release etc. according to the previous research arti- cles, the research done by Someren et al. (1997), the study was done by assessing the circadian sys- tem, and the temperature of the body and the results were observed. The morningness-eveningness scale is used to measure the preferred timing of rising and bedtime as well as physical and mental perfor- mance and alertness after rising and after differ- ent activities. According to the studies done and 686 © International Journal of Research in Pharmaceutical Sciences