5. Bacchetta J, Bardet C, Prié D. Physiology of FGF23 and overview of genetic diseases associated with renal phosphate wasting. Metabolism 2020; 103S: 153865 MO1030 AKI AWARENESS AND SURVIVAL IN PAEDIATRIC PATIENTS IN A WESTERN ROMANIA EMERGENCY HOSPITAL—A 7 YEARS RETROSPECTIVE COHORT STUDY Flavia Chisavu 1 , Mihai Gafencu 2 , Lazar Chisavu 3 , Ramona Stroescu 2 , Adelina Mihaescu 4 , Oana-Marina Schiller 5 and Adalbert Schiller 4 1 Emergency Clinical Hospital for Children « Louis Turcanu » Timisoara, Romania, Paediatric Nephrology, Timisoara, Romania, 2 University of Medicine and Pharmacy Victor Babes Timisoara, Romania, Paediatrics, Timisoara, Romania, 3 University of Medicine and Pharmacy Victor Babes Timisoara, Romania, Nephrology, Timisoara, Romania, 4 University of Medicine and Pharmacy Victor Babes Timisoara, Romania, Nephrology, Timisoara, Romania and 5 Avitum BBraun Timisoara Romania, Nephrology, Timisoara, Romania BACKGROUND AND AIMS: Acute kidney injury (AKI) is a globally increasing healthcare problem being usually associated with low awareness and high mortality. Several large studies have drawn attention to the increasing cases of AKI in the paediatric population, mostly in the neonatal setting but also in critically ill patients and young adults. It was suggested that increased awareness could lead to early diagnosis and intervention, therefore improved survival. METHOD: We performed a retrospective cohort study in ‘Louis Turcanu’ Emergency County Hospital for Children in Timisoara, Romania. Data have been extracted from the hospital electronic database, between 1 January 2014 and 31 December 2020. The cohort included 127 457 patients (aged 1 day–18 years) who had at least two serum creatinine levels determined during the same hospital admission. AKI was defned and staged according to Kidney Disease Improving Global Outcomes (KDIGO) guidelines (and 2021 Consensus conference). AKI awareness was considered the recognition of AKI diagnosis during admission as noted in the medical records according to ICD-10 Clinical Modifcation codes (N17.0, N17.1, N17.2, N17.8, N19, N99.0 and P96.0). AKI non-awareness was considered in patients presenting AKI criteria without diagnoses recognition in the medical records. We considered baseline serum creatinine the lowest serum creatinine value in 7 days from admission. RESULTS: Over the 7-year period, 1867 patients developed AKI out of 127 457 hospital admissions. The overall AKI incidence was 1.46% and the annual incidence increased 3.95-fold during the 7 years (from 0.6% in the frst year to 2.37% in the seventh). Staging AKI according to Acute Kidney Injury Network (AKIN), stage 1 was identifed by us in 23.2% of the AKI cases, stage 2 in 31.3% and stage 3 in 45.5%. AKI awareness (as defned above) was 27.5% (overall), being signifcantly increased in premature babies (P < .012), full-term neonates (P < .0001) and toddlers (P < .0001). In AKI stages 1 and 2 the diagnosis of AKI (included in the patient’s documents according to ICD 10) was less frequent as compared to stage 3. So, we considered that AKI awareness is signifcantly lower in early AKI stages (1 and 2) (i.e.16.9 and 19.7% respectively) as compared with late AKI (stage 3) 38.3% (P < .001). Only 19 patients (1.01%) required renal replacement therapy (RRT). During the 7-year period, the all-cause mortality in our cohort was 0.32% (410 patients died) being 0.13% in the no AKI patients and 12.8% in the AKI group (57.89% in patients treated with RRT). Odds ratio (OR) of death in the AKI diagnosed patients (aware and non-aware) was 107.67 versus non-AKI patients (P < .0001). The risk of death in the AKI aware group was 3.3 higher versus AKI non-aware group (P < .001). These not expected, reverse results, are attributable to a very low awareness (as defned by us in Methods) in the early stages of AKI. A higher mortality rate was associated with AKIN stage 3—OR of 1.53 (P < .001). The average length of hospital stay was signifcantly higher in AKI patients (20.79 days) as compared with the no AKI group (5.74 days). CONCLUSION: The awareness of AKI in children remains a problem worldwide with implications on the survival of patients. Being aware of AKI means early identifying the risk of AKI, early diagnosis and early intervention. As it was presented above late diagnosis and awareness are associated with high mortality rate and the need for interventions (RRT) associated with high mortality risk. MO1031 BURNOUT SYNDROME AMONG PAEDIATRIC NEPHROLOGISTS—REPORT ON ITS PREVALENCE, SEVERITY AND PREDISPOSING FACTORS Ewa Pawlowicz-Szlarska 1 , Piotr Skrzypczyk 2 , Malgorzata Sta ´ nczyk 3 , Malgorzata Pa ´ nczyk-Tomaszewska 2 and Michal Nowicki 1 1 Medical University of Lodz, Department of Nephrology, Hypertension and Kidney Transplantation, Lodz, Poland, 2 Medical University of Warsaw, Department of Paediatrics and Nephrology, Warsaw, Poland and 3 Polish Mother’s Memorial Hospital Research Institute, Department of Paediatrics, Immunology and Nephrology, Lodz, Poland BACKGROUND AND AIMS: Burnout is an occupational-related syndrome comprising emotional exhaustion, depersonalization and reduced feelings of work-related personal accomplishments. Addressing and mitigating burnout is essential for avoiding high workforce turnover, patient dissatisfaction and a lower quality of care. There are some reports on burnout among adult nephrologists and general paediatricians, but little has been known about burnout among paediatric nephrologists. The aim of our study was to assess the prevalence and severity of burnout syndrome among Polish paediatric nephrologists. METHOD: A 25-items online survey consisting of abbreviated Maslach Burnout Inventory and additional self-created questions about work-related factors was completed by 97 physicians afliated with the Polish Society of Paediatric Nephrology. 75.3% of them were women, the median time of professional experience in the study group was 15 years. RESULTS: High level of emotional exhaustion, depersonalization and reduced feeling of personal accomplishments was observed in 39.2%, 38.1% and 21.6% of participants, respectively. 26.8% of participants presented at least a medium level of burnout in all three dimensions and 8.2% of them presented high three-dimensional burnout. No associations of burnout intensity and gender, job seniority and the use of holiday leave were found. 41.2% of participants stated, that they would like to take part in burnout prevention and support programme. According to the study participants, excessive bureaucracy in healthcare systems, rush and working overtime were the main job-related problems that can infuence burnout intensity. CONCLUSION: Burnout is an important factor in the professional landscape of paediatric nephrology. Actions aiming at reducing the risk of occupational burnout among paediatric nephrologists should be applied both at personal and institutional levels. MO1032 ASSESSING THE EFFECTIVENESS OF READY STEADY GO—PEEER PROJECT YOUTH WORK IN MEETING THE PSYCHOSOCIAL NEEDS OF CHILDREN AND YOUNG PEOPLE Arvind Nagra 1 , Sarah Shameti 1 , Eleanor Stubbs 1 , Rodney Gilbert 1 , Mushfaquar Haq 1 , Caroline Anderson 1 , Evgenia Preka 1 , Alejandra Recio-Saucedo 2 and Anne-Sophie Darlington 3 1 Southampton Children’s Hospital, Paediatric Nephro-Urology, Southampton, UK, 2 University of Southampton, Faculty of Health Sciences, Southampton, UK and 3 University of Southampton, Faculty of Health Sciences, Southampton, UK BACKGROUND: Studies show that young people (YP) with chronic kidney disease do less well than their well peers in terms of mental health and employability. In the UK 30% of YP on renal replacement therapy have mental health issues compared to 15% of the general population and more are unemployed compared with their well peers. Many of the issues start in childhood as studies show that children with chronic kidney disease have signifcant psychosocial issues including: • Depression • Anxiety • Educational difculties • Relationship issues • Low self-esteem • Social isolation, family dependency • Professional restriction To address these issues, we developed the PEEER project to help improve Patient Empowerment, self-Esteem, Employability and Resilience. • PEEER brings YP together to participate in fun activities to help build self- esteem, develop an ‘I can do’ attitude, build a peer support group and reduce the sense of isolation patients feel. Table 1. Abstract i751 Downloaded from https://academic.oup.com/ndt/article/37/Supplement_3/gfac089.009/6577896 by guest on 26 June 2023