Development of MiniCEX to assess nurses' clinical skills concerning medication The clinical practice of nurses requires the development of skills that directly imply the safety and quality of care. The Mini Clinical Evaluation Exercise (MiniCEX) is a tool for evaluating clinical practice in real contexts that helps the self-regulation aspect of the learning experience based upon feedback at the end of each evaluated moment. This study aimed to build a MiniCEX for nurses and undergraduate nursing students, on clinical skills in the process of preparing, administering, and monitoring medications. This is developmental research. The theories that supported the methodological route were: Patricia Benner's model for the development of clinical skills in nursing; David Kolb's Experiential learning theory; the Medication System described by Cassiani et al.; the Patient Classification Instrument per complexity of nursing care, according to the area of care, proposed by Fugulin, Gaidzinski and Kurcgant; and, the assumptions of the National Patient Safety Program, focusing on safety in medication practice. Thus, three competencies were organized: preparation, administration, and monitoring of patients using drugs. As feedback is essential in MiniCEX, the studies by Hattie and Timperley, and Hattie and Clarke on feedback in the teaching-learning processes were considered. Thus, it is possible to characterize the MiniCEX outlined as an instrument for educational assessments, capable of developing specific nursing skills, which can be used both for nursing students during the practice of internships, as well as for monitoring and assessing the medicating skills of novice nurses to a given clinical setting. Keywords: Skill-Based Education. Educational Evaluation. Clinical procedures. Clinical skill. Nursing. INTRODUCTION Nursing professionals perform multiple tasks with specific skills and knowledge. Therefore, in their training process, they need to be prepared and encouraged to develop a diversity of competences, defined as a complex of knowledge on how to act, combining skills, knowledge, attitudes, and available resources, as well as the ability to apply this knowledge in a given situation 1 . In this sense, the role of nurses requires the acquisition of clinical skills, which underlie their actions and decision making during their practice, and which directly involve the quality and safety of the care provided. In the 1990s, the American Board of Internal Medicine (ABIM) developed a practical and quick tool to support the educational assessment of medical residents, the Mini Clinical Assessment Exercise (MiniCEX). The instrument consisted of a scale that assessed six essential skills of students: 1) interviews and clinical history skills; Abstract Bruno César Fernandes* Ely Bueno da Silva Bispo* Jackeline Camargos Pereira* Marcos Antonio Nunes Araujo* Rogério Dias Renovato* Mundo da Saúde 2020,44:465-474, e0092020 465 *Universidade Estadual de Mato Grosso do Sul, Dourados, Mato Grosso do Sul, Brasil. E-mail: brunoanaisafernandes@gmail.com DOI: 10.15343/0104-7809.202044465474