International Journal for Innovation Education and Research www.ijier.net Vol:-10 No-4, 2022 International Educative Research Foundation and Publisher © 2022 pg. 181 Biological Assessments of Baccharis dracunculifolia DC from a Cerrado fragment in Central-West Brazil José Amarildo Avanci Júnior Postgraduate - Federal University of Mato Grosso do Sul ORCID: https://orcid.org/0000-0002-8834-2173 E-mail: amarildo.avanci@gmail.com Marcelo Fontes da Silva Postgraduate - Federal University of Mato Grosso do Sul ORCID: https://orcid.org/0000-0001-8736-762X E-mail: marcelofontes@hotmail.com Jéssica Carolina Garcia Avanci Moretti Postgraduate - Federal University of Mato Grosso do Sul ORCID: https://orcid.org/0000-0001-5428-4924 E-mail: jessica.avanci@icloud.com Rosemary Matias Coelho Postgraduate - Federal University of Mato Grosso do Sul ORCID: https://orcid.org/0000-0002-0154-1015 E-mail: rosematias@uniderp.br Danielle Bogo Postgraduate - Federal University of Mato Grosso do Sul ORCID: https://orcid.org/0000-0003-0233-3047 E-mail: danielle.bogo@ufms.br Abstract Baccharis dracunculifolia is used as an herbal medicine, and green propolis, synthesized by Apis mellifera bees from it, has inflammatory, antioxidant and antimicrobial principles. This bee product is effective in combating a series of microorganisms in folk medicine, so it is essential to develop research to prove this effectiveness. The objectives of the work were to analyze the microbiological profile, dose the flavonoids and verify the plant's antioxidant activity. The aerial parts were collected in a fragment of cerrado sul- mato-grossense and processed, obtaining extracts with hexane, ethyl acetate and ethanol. For microbiological analysis, Staphylococcus aureus bacteria was seeded in agar and filter discs were soaked with the extracts and, together with the control group, were placed in Petri dishes for subsequent measurement of inhibition halos. To measure the flavonoids and evaluate the antioxidant activity,