Accepted Manuscript Title: Quantitative imaging of platinum-based antitumor complexes in bone tissue samples using LA-ICP-MS Authors: Barbara Crone, Lukas Schlatt, Robin Abraham Nadar, Natasja Wilhelmina Maria van Dijk, Nicola Margiotta, Michael Sperling, Sander Leeuwenburgh, Uwe Karst PII: S0946-672X(18)30522-4 DOI: https://doi.org/10.1016/j.jtemb.2019.04.011 Reference: JTEMB 26327 To appear in: Received date: 27 August 2018 Revised date: 21 March 2019 Accepted date: 18 April 2019 Please cite this article as: Crone B, Schlatt L, Nadar RA, van Dijk NWM, Margiotta N, Sperling M, Leeuwenburgh S, Karst U, Quantitative imaging of platinum-based antitumor complexes in bone tissue samples using LA-ICP-MS, Journal of Trace Elements in Medicine and Biology (2019), https://doi.org/10.1016/j.jtemb.2019.04.011 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.