7 A journal of the AMERICAN Journal of Engineering, Mechanics and Architecture www. grnjournal.us AMERICAN Journal of Engineering, Mechanics and Architecture Volume 01, Issue 04, 2023 ISSN (E): 2993-2637 THE EFFECTS OF OSCILLATING ELECTROMAGNETIC RADIATION ON KIDNEY FUNCTION IN PLASMODIUM-INFECTED MICE Abayomi Simeon Alade Physics and Electronics Department, Adekunle Ajasin University Akungba Akoko, Ondo State, Nigeria Email: abayomy.alade@gmail.com Abstract The interaction of electromagnetic fields (EMFs), particularly the oscillating magnetic field (OSMF), and living things has recently received a lot of attention. Despite the fact that the effects of EMFs on numerous physiological systems have been thoroughly studied, there has been little research on the potential effects of EMFs on kidney parameters in the context of malaria parasite infection. This study looked at how EMF (OSMF) exposure affected kidney parameters in mice infected with malaria parasites. Mice infected with Plasmodium berghei were randomly divided into five EMF-exposed groups (10mT, 15mT, 20mT, 30mT, and 40mT) and four control groups (Treatment control, Negative control, Positive control, and Normal control). The Treatment control group was not infected but was exposed to 40mT EMF, while the Negative control group was infected and exposed to 40mT EMF, The negative control group was infected but not treated, whereas the positive control group received antimalarial treatment (arthemether lumenfantrine). The Normal control group was not infected and was not treated. The EMF-exposed groups were exposed to a 50 Hz electromagnetic field of varying magnitudes for six hours per day for five days. After five days of EMF exposure, the EMF-exposed and control groups were sacrificed, and their kidney tissues were collected for analysis. The conventional biomarkers for kidney function, serum creatinine and blood urea nitrogen, were measured. In addition, parasite density was determined. In mice infected with the malaria parasite, results show that EMF exposure significantly altered kidney parameters. The EMF- exposed group had higher levels of blood urea nitrogen than the control groups. Keywords: Electromagnetic radiation, Oscillating magnetic field, kidney parameters, Plasmodium berghei, blood urea nitrogen, serum creatinine, Parasite density. Introduction According to WHO annual reports, malaria continues to be a significant global health burden, with approximately 229 million cases reported worldwide in 2019 (Menkin-Smith & Winders, 2022). Plasmodium, the malaria parasite, invades and replicates within erythrocytes, leading to the release of various metabolic byproducts and inducing systemic inflammatory responses (Gaur & Chitnis., 2011). These pathological processes can contribute to organ dysfunction, including renal impairment, which has been recognized as a frequent complication in severe malaria cases (Plewes, Turner & Dondorp, (2018). In recent years, the potential impact of electromagnetic fields (EMFs) on human health has emerged as a topic of considerable scientific interest. EMFs are generated by both natural and human-made sources, such as power