Chowdhury P, Pandey V, Avasthi R, Kandukuri MK, Giri S, Sharma S. Multi-factorial risk stratification in Acute Coronary Syndrome. IAIM, 2016; 3(1): 36-45. Page 36 Original Research Article Multi-factorial risk stratification in Acute Coronary Syndrome Partho Protim Chowdhury 1 , Vanita Pandey 2 , Rajnish Avasthi 3 , Kandukuri Mahesh Kumar 2* , Subhash Giri 3 , Satendra Sharma 4 1 Consultant Cardiologist, Meditrina Hospital, Jamshedpur, Jharkhand, India 2 Assistant Professor, Department of Pathology, Malla Reddy Institute of Medical Sciences (MRIMS), Hyderabad, Telangana State, India 3 Professor, Department of Medicine, University College of Medical Sciences (UCMS) and Guru Teg Bahadur (GTB) Hospital, Delhi, India 4 Professor, Department of Pathology, University College of Medical Sciences (UCMS) and Guru Teg Bahadur (GTB) Hospital, Delhi, India * Corresponding author email: doctormaheshgoud@gmail.com International Archives of Integrated Medicine, Vol. 3, Issue 1, January, 2016. Copy right © 2016, IAIM, All Rights Reserved. Available online at http://iaimjournal.com/ ISSN: 2394-0026 (P) ISSN: 2394-0034 (O) Received on: 21-12-2015 Accepted on: 31-12-2015 Source of support: Nil Conflict of interest: None declared. How to cite this article: Chowdhury P, Pandey V, Avasthi R, Kandukuri MK, Giri S, Sharma S. Multi-factorial risk stratification in Acute Coronary Syndrome. IAIM, 2016; 3(1): 36-45. Abstract Background: ST elevated myocardial infarction (STEMI), non-ST elevated myocardial infarction (NSTEMI) and unstable anginas (UA) are continual spectrum of coronary artery disease (CAD). These are terminal events arising as a result of coronary artery atherosclerosis and superimposed thrombosis. Materials and methods: A prospective study in which a total of 91 patients of either sex aged 20 to 60 years were recruited, of which 30 were STEMI, 31 were NSTEMI/ unstable angina and 30 were age and sex matched healthy controls. Patients with following complaints of maximum 24 hours duration were registered in the emergency department and were included in the study (ACC/AHA Guidelines, 2002). Results: In the present study, 91 subjects were recruited from medical emergency department. All of the subjects were meeting the inclusion criteria. Of the total 91 subjects 30 were of STEMI (Group 1), 15 were of NSTEMI (Group 2), 16 were of unstable angina (Group 3) and 30 were controls (Group 4). Conclusion: In patients of ACS, MPO is raised as compared to controls. Also in complicated ACS, irrespective of other risk factors, MPO was significantly raised as compared to controls and can be used to predict immediate clinical complication. There is no significant association between MPO, hs