Special Issue (September) Online - 2455-3891 Print - 0974-2441 International Conference of Pharmacy (ICP-2017) at School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India TREND OF USE OF DIFFERENT ANTIMIGRAINE MEDICATIONS AND AWARENESS OF MIGRAINE, SURVEY BASED STUDY IN JALANDHAR AMANDEEP KAUR 1 , HARMANPREET SINGH 2,3 *, SUKSHAM GUPTA 1 , JASJEET KAUR NARANG 4 , YASH PAUL SINGLA 5 , AVNEET KAUR 6 Received: 14 July 2017, Revised and Accepted: 25 July 2017 ABSTRACT Objective: A brain disease, migraine is a special type of headache that causes highly intense, throbbing quality pain in half head or any one side of the head. It may be due to several reasons such as food intake, sleep disturbance, and stress or tension. Hormonal disturbance can result in migraine. There is no specific treatment for migraine. Analgesics or pain killers may prove effective in migraine. To prevent it cautions must be taken. Our study aims to find out the awareness and prevalence of migraine among students of different schools, colleges, universities, and professional institutes of Jalandhar city. Further, the drug consumption pattern of most prominent used antimigraine medications was also calculated. Method: The cross–sectional data were collected through a questionnaire from the random sample in the month from August 2016 to November 2016 in Jalandhar. To check the drug consumption, daily defined dose (DDDs) or drug usage has been calculated using the DDD recommended by the World Health Organization. Results: According to our survey, 80% candidates have heard about the term “migraine.’’ 36% candidates are aware about the causes, 58% aware about the signs and symptoms of migraine while 23% candidates are aware about the treatment. The overall awareness rate of migraine in candidates is about 45%. Conclusion: The prevalence of migraine is more in women than men by a factor of about 3:1. Triptans are mostly found to be effective for the treatment of migraine. The main cause of migraine was found to be stress or tension and the common symptom of migraine was throbbing or pulsating pain on one side of the head. Keywords: Migraine, Daily defined dose, Triptans. INTRODUCTION Migraine is a periodic headache, unilateral or bilateral, causing pulsating or throbbing pain which gets worsted by physical activities and/or emotional stress [1]. It causes one sided intense pain of head [2]. Migraine is the 5 th most important cause for women among all diseases worldwide causing disability, and for men, it is one of the top 20 diseases [3]. According to the Global Burden of Disease Survey 2000 (GBD 2000), conducted by the World Health Organization (WHO), migraine was the 19 th most disabling illness in the world, but according to its updating in 2013 (GBD 2013), it is the 6 th highest disease worldwide causing disability [4,5]. After tension headache, the second general kind of primary headaches are the migraine headaches. A headache which is not caused by another disease or condition is called a primary headache [6]. It is considered as persistent unilateral headache united with neurologic and gastrointestinal disturbances that can severely influence the quality of living and daily activities [7]. According to Best Places President Bert Sperling, migraine is most commonly found than asthma and diabetes, however, there are still many people who have migraine symptoms, but they don’t get medical help [8]. Migraine also raises the possibility for further physical and psychiatric circumstances [9]. Hence, we conduct a survey to check the awareness and prevalence of migraine in population of Jalandhar. Our aims were also to enhance the awareness about migraine and to check the most prominent used antimigraine medications. The cross–sectional and random method was used to collect data from the sample through a specially planned questionnaire. Phases of a migraine Migraine usually starts in childhood, adolescence or early adulthood. Migraine may involve following four phases [2,10,11]. Prodrome (early warning) It takes place hours to days before migraine without headache. It involves some changes such as neck rigidity, constipation/diarrhea, and mood fluctuations. Aura (pre-migraine) It is neurological phenomena which involve visual disturbances just before the headache. Aura may arise before or throughout migraines. In general, people experience migraines without aura. Occasionally auras can also include sensory, motor, or verbal disturbances. These symptoms strengthen over several minutes and last for 20-60 minutes. Pain phase (during headache/headache phase) If migraine is untreated, it generally lasts from 4 to 72 hrs. The frequency of headache occurs, changes from individual to individual. During a migraine, you may be subjected to nausea and vomiting. Research Article 1 Department of School of Pharmaceutical Sciences, Lovely Professional University, Phagwara - 144411, Punjab, India. 2 Department of ? I. K. G Punjab Technical University, Kapurthala, Punjab, India. 3 Department of Pharmaceutics, Lovely Institute of Technology (Pharmacy), Lovely Professional University, Phagwara - 144411, Punjab, India. 4 Department of , Khalsa College of Pharmacy, Amritsar - 143001, Punjab, India. 5 Controller of Examinations, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India. 6 Department of Universiti Tunku Abdul Rahman, Kuala Lumpur, Malaysia. Email: harmanpreetmadaan@gmail.com © 2017 The Authors. Published by Innovare Academic Sciences Pvt Ltd. This is an open access article under the CC BY license (http://creativecommons. org/licenses/by/4. 0/) DOI: http://dx.doi.org/10.22159/ajpcr.2017.v10s4 .21333