1 GSJ: Volume 9, Issue 5, May 2021, Online: ISSN 2320-9186 www.globalscientificjournal.com The Prevalence of the Transfusion Transmissible Infections (TTI) among Donors Studied in a Tertiary Level Hospital in Bangladesh Tanzila Rawnuck 1 , Md Selim Reza 2 , Rajib Ahmed 3 , Mohammad Fatteh-Ul- Islam 4 , Rumana Hasan Sharmi 5 , Shabiha Monwar 6 Abstract Background: Transfusion transmissible infections can be a risk for health care professionals, according to World Health Organization (WHO) about 3 million workers are getting exposed to these kinds of infections each year. The overall prevalence of transfusion-transmitted infections ranges between 2.79% and 18.7%. Objectives: This study aimed to identify the prevalence of transfusion transmissible infections among prospective donors. Materials and Methods: This prospective analytic study was conducted among 3963 donors at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Detection of HBsAg, Anti-HCV, Anti-HIV, Anti-Treponema, and Anti-Malaria was done by Immunochromatographic test (ICT), Syphilis Fast latex agglutination, RDT test, and reconfirmed by ELISA. Results: Among 3963 donors the transfusion transmissible infection’s seroprevalence was 47(1.18%). The prevalence of HBV, HCV, HIV, Syphilis and Malaria were found to be 30(0.76%), 09(0.23%), 03(0.07%), 04(0.10%) and 01(0.02%) respectively. Conclusion: There should be a strict guideline in donor selection to avoid TTI. Implementation of a more sensitive testing methodology should help to detect infection in donors accurately, even during the window period, which may reduce TTI. Keywords: Transfusion transmissible infections, HBV, HCV, HIV, Syphilis, and Malaria. Number of Tables: 02; Number of References:18; Number of Correspondence: 05. 1. Assistant Professor, Dept of Pathology with Microbiology, Dhaka Dental College, Dhaka, Bangladesh. 2. Assistant Professor, National Institute of Traumatology & Orthopaedic Rehabilitation (NITOR), Dhaka, Bangladesh. 3. Assistant Professor, Dept of Microbiology, Colonel Malek Medical College, Manikganj, Bangladesh. 4. Consultant, Dept of Transfusion Medicine, Rajshahi Medical College, Rajshahi, Bangladesh. 5. Lecturer, Dept of Community Medicine, Colonel Malek Medical College, Manikganj, Bangladesh. 6. Assistant Professor, Dept of Microbiology, Marks Medical College, Dhaka, Bangladesh. Correspondence: Dr Tanzila Rawnuck. E-mail:drrawnuck@gmail.com GSJ: Volume 9, Issue 5, May 2021 ISSN 2320-9186 468 GSJ© 2021 www.globalscientificjournal.com