_____________________________________________________________________________________________________ *Corresponding author: Email: zigedv@fuotuoke.edu.ng, zigedouye@gmail.com; Int. J. Path. Res., vol. 12, no. 2, pp. 9-15, 2023 International Journal of Pathogen Research Volume 12, Issue 2, Page 9-15, 2023; Article no.IJPR.97237 ISSN: 2582-3876 Antibiotics Profile and Public Health Implication of Pathogenic Enteric Bacteria Associated With Poultry Stool Douye Victor Zige a* and Faith Iyeoma Omeje a a Department of Microbiology, Federal University Otuoke, P.M.B. 126, Yenagoa, Bayelsa State, Nigeria. Authors’ contributions This work was carried out in collaboration between both authors. Both authors read and approved the final manuscript. Article Information DOI: 10.9734/IJPR/2023/v12i2221 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/97237 Received: 02/01/2023 Accepted: 03/03/2023 Published: 24/03/2023 ABSTRACT Poultry waste are not properly disposed and most rural farmers make use of it as manure therefore poultry wastes may serve as source of enteric organism capable of infecting humans. The antibiotic resistance from these bacteria can be transferred to natural microbial community as a result of involvement of antibiotics in poultry farming. This research was carried out to assess the multidrug resistant pattern of enteric bacteria in poultry stool dropping. samples of poultry droppings were obtained from a free-range commercial poultry farm in Otuoke, Bayelsa State, Nigeria. Samples were cultured on selective and differential media. 16 isolates of enteric bacteria were obtained from poultry stool droppings. The isolates identified were of four genera. Salmonella species which is predominant 6(37%) followed by Escerichia coli 5(31%) Proteus species 3(19%) and Kiebsiella species 2(13%). Antibiotic susceptibility testing was carried out using the disk diffusion technique. Gram negative antibiotics including crioxacin cefprozil, nitrofuration, ceftazidime co-trimoxazole, genetamicin, cefuroximo. The resistant pattern in among the gram negative pathogens revealed that more than 98% were resistant to nitrofuratioin cefprozil, gentamicin and augumentin while 12.89% resistant to certazidime, 90.10% resistant to augmentin, 15.32% cefuroxime, 12.30% co- Original Research Article