Lamya H. Al-Wahaibi, Mohammed S. M. Abdelbaky, Santiago Garcia-Granda, Guido J. Reiss, Edward R. T. Tiekink and Ali A. El-Emam* N′-[(1E)-(4–Fluorophenyl)methylidene] adamantane-1-carbohydrazide, C 18 H 21 FN 2 O https://doi.org/10.1515/ncrs-2023-0195 Received April 23, 2023; accepted June 14, 2023; published online July 5, 2023 Abstract C 18 H 21 FN 2 O, triclinic, P 1 (no. 2), a = 10.6377(5) Å, b = 14.4869(7) Å, c = 21.0557(13) Å, α = 98.583(5)°, β = 91.979(4)°, γ = 90.101(4)°, V = 3206.5(3) Å 3 , Z = 8, R gt (F ) = 0.0815, wR ref (F 2 ) = 0.1930, T = 172 K. CCDC no.: 2269765. The crystallographic images is shown in the figure. Table 1 contains crystallographic data and Table 2 contains the list of the atoms including atomic coordinates and displacement parameters. 1 Source of material To a solution of adamantane-1-carbohydrazide (1.94 g, 0.01 mol), in ethanol (10 mL), 4-fluorobenzaldehyde (1.24 g, 0.01 mol) was added, after which the mixture was heated under reflux for 1 h. On cooling, the separated crude product was filtered, washed with cold ethanol, dried and recrys- tallised from ethanol to yield 2.76 g (92 %) of the title compound as colourless prisms [5]. M.pt 476–478 K. 1 H NMR (DMSO-d 6 , 500.13 MHz): δ 1.66–1.69 (m, 6H, adamantane–H), 1.88 (s, 6H, adamantane–H), 2.01 (s, 3H, adamantane–H), 5.67 (s, 1H, NH), 7.27–7.29 (m, 2H, Ar–H), 7.85–7.87 (m, 2H, Ar–H), *Corresponding author: Ali A. El-Emam, Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt, E-mail: elemam@mans.edu.eg. https://orcid.org/0000-0002-9325-9497 Lamya H. Al-Wahaibi, Department of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia. https://orcid.org/0000-0001-7537-1840 Mohammed S. M. Abdelbaky and Santiago Garcia-Granda, Department of Physical and Analytical Chemistry, Faculty of Chemistry, Oviedo University–CINN, Oviedo 33006, Spain Guido J. Reiss, Inorganic Chemistry and Structural Chemistry, Heinrich– Heine–Universitẗ; Ds ̈ seldorf, 40225 Düsseldorf, Germany. https://orcid.org/ 0000-0002-3004-3955 Edward R. T. Tiekink, Research Centre for Crystalline Materials, School of Medical and Life Sciences, Sunway University, 47500 Bandar Sunway, Selangor Darul Ehsan, Malaysia. https://orcid.org/0000-0003-1401-1520 Z. Kristallogr. - N. Cryst. Struct. 2023; aop Open Access. © 2023 the author(s), published by De Gruyter. This work is licensed under the Creative Commons Attribution 4.0 International License.