Vol.:(0123456789) 1 3
Pediatric Cardiology
https://doi.org/10.1007/s00246-018-1929-1
ORIGINAL ARTICLE
Comparison of Balloon Dilatation and Surgical Valvuloplasty in Non-
critical Congenital Aortic Valvular Stenosis at Long-Term Follow-Up
Sezen Ugan Atik
1
· Ayşe Güler Eroğlu
1
· Betül Çinar
2
· Murat Tuğberk Bakar
3
· İrfan Levent Saltik
1
Received: 17 March 2018 / Accepted: 6 June 2018
© Springer Science+Business Media, LLC, part of Springer Nature 2018
Abstract
The two main modalities used for congenital aortic valvular stenosis (AVS) treatment are balloon aortic valve dilatation
(BAD) and surgical aortic valvuloplasty (SAV). This study evaluates residual and recurrent stenosis, aortic regurgitation
(AR) development/progression, reintervention rates, and the risk factors associated with this end point in patients with non-
critical congenital AVS who underwent BAD or SAV after up to 18 years of follow-up. From 1990 to 2017, 70 consecutive
interventions were performed in patients with AVS, and 61 were included in this study (33 BADs and 28 SAVs). There were
no signifcant diferences in age, sex distribution, PSIG, and AR frequency between the BAD and SAV groups. Bicuspid
valve morphology was more common in the BAD group than the SAV group. There was no statistically signifcant diference
between PSIGs and AR development or progression after intervention at the immediate postoperative echocardiography of
patients who underwent BAD or SAV (p = 0.82 vs. p = 0.29). Patients were followed 6.9 ± 5.1 years after intervention. The
follow-up period in the SAV group was longer than that of the BAD group (9.5 ± 5.4 vs. 5.5 ± 4.4 years, p = 0.003). There
was no statistically signifcant diference in the last echocardiographic PSIG between patients who underwent SAV or BAD
(51.1 ± 33.5 vs. 57.3 ± 35.1, p = 0.659). Freedom from reintervention was 81.3% at 5 years and 57.5% at 10 years in the BAD
group and 95.5% at 5 years and 81.8% at 10 years in the SAV group, respectively (p = 0.044). There was no diference in
postprocedural immediate PSIG and last PSIG at follow-up and the development/progression of AR between patients who
were treated with BAD versus SAV. However, long-term results of SAV were superior to those of BAD, with a somewhat
prolonged reintervention interval.
Keywords Aortic valvular stenosis · Balloon aortic valve dilatation · Echocardiography · Surgical aortic valvuloplasty
Introduction
Aortic valvular stenosis (AVS) accounts for approximately
7.7% of all congenital heart diseases [1]. The two main treat-
ment modalities used for AVS in the pediatric population are
surgical aortic valvuloplasty (SAV) and balloon aortic valve
dilatation (BAD) [2, 3]. Surgical valvuloplasty, introduced
by Lillehei in 1956, was the only therapeutic option until
1983, when Lababidi introduced BAD [2, 3]. In the current
era, both treatment modalities are available with preference
dependent on the institution [4–8]. However, there are a
limited number of long-term follow-up studies that allow
appropriate comparison of BAD and SAV in patients with
congenital AVS [9–11]. Consequently, there is still no con-
sensus regarding the most efcacious initial treatment.
This study evaluates residual and recurrent stenosis, aor-
tic regurgitation (AR) development and progression, reinter-
vention rates, and risk factors associated with this end point
in patients with non-critical congenital AVS who underwent
BAD or SAV during long-term follow-up.
Materials and Methods
Since 1990, 388 patients with non-critical congenital
AVS were evaluated by echocardiography at our institu-
tion. Patients with incomplete medical records, abnormal
* Sezen Ugan Atik
sezenugan@hotmail.com
1
Department of Pediatric Cardiology, İstanbul University
Cerrahpaşa Medical Faculty, Istanbul, Turkey
2
Department of Pediatrics, İstanbul University Cerrahpaşa
Medical Faculty, Istanbul, Turkey
3
Department of Public Health, İstanbul University Cerrahpaşa
Medical Faculty, Istanbul, Turkey