1 Supporting Information for Efficient Syntheses of 5-Aminoalkyl-1H-tetrazoles and of Polyamines Incorporating Tetrazole Rings Constantinos M. Athanassopoulos * , Thomas Garnelis, Dimitrios Vahliotis and Dionissios Papaioannou Department of Chemistry, University of Patras, GR 265 00, Patras, Greece General Melting points were determined with a Buchi SMP-20 apparatus and are uncorrected. 1 H- NMR spectra were obtained at 400.13 MHz and 13 C-NMR spectra at 100.62 MHz on a Bruker DPX spectrometer. CDCl 3 and tetramethylsilane (TMS) were used as the solvent and internal standard, respectively, unless otherwise stated. Chemical shifts are reported in units, parts per million (ppm) downfield from TMS. The assignments of the 1 H spectra are based on chemical shift arguments, analysis of coupling patterns and signal intensities whereas the 13 C spectra were assigned taking into consideration chemical shift arguments. Electron-spray ionization (ESI) mass spectra were recorded on a Micromass-Platform LC spectrometer using MeOH as solvent. The MALDI high-resolution MS (HR-MS) experiments were carried out in a MALDI-TOF-TOF A/B 4700 proteomics instrument. Microanalyses were performed on a Carlo Erba EA 1108 CHNS elemental analyzer in the Center of Instrumental Analysis of the University of Patras. Flash column chromatography (FCC) was performed on Merck silica gel 60 (230-400 mesh) and TLC on 60 Merck 60 F 254 films (0.2 mm) precoated on aluminium foil. Spots were visualized with UV light at 254 nm and the ninhydrin agent. All solvents (Merck) were dried and/or purified according to standard procedures prior to use. Anhydrous Na 2 SO 4 was used for drying organic solvents, unless otherwise indicated, and subsequently solvents were routinely removed at ca. 40 o C under reduced pressure (water aspirator). All reagents employed in the present work were purchased from either Aldrich or Fluka and used without further purification with the exception of TFA-mediated deprotections, all other reactions were routinely carried out under an atmosphere of Ar.