AJR:167, October 1996 877
Small (3 cm) Hyperechoic Renal
Masses: Comparison of Helical and
Conventional CT for Diagnosing
Angiomyolipoma
Stuart 6. Silverman1
Gregory D. N. Pearson
Steven E. Seltzer
Maria Polger
Clare M. C. Tempany
Douglass F. Adams
Douglas L. Brown
Phillip F. Judy
OBJECTIVE. Because hyperechoic renal masses may represent angiomyolipomas or small
renal cancers, CT is often used to reveal the fatty component, which allows diagnosis of angio-
myolipoma in most cases. Because conventional CT can fail to reveal fat in angiomyolipomas 3
cm or smaller, we conducted a study to determine whether helical CT would improve our detec-
tion of fat and allow more of these masses to be diagnosed as angiomyolipomas.
SUBJECTS AND METHODS. We used helical and conventional CT to examine 20
masses (5-29 mm in diameter) in 17 patients who had a small hyperechoic mass detected
sonographically. Densitometry was performed by three readers and the mean attenuation val-
ues were compared.
RESULTS. Of the 20 masses, we diagnosed angiomyolipoma in 16 masses using helical
CT and in 14 masses using conventional CT. In 1 1 masses, we found the measured attenua-
tion values to be more negative on helical CT scans than on conventional CT scans. In five
masses, we found the opposite to be true. In the remaining four masses, we were unable to
diagnose angiomyolipoma. Of the masses that we diagnosed as angiomyolipoma, the mean
attenuation value when examined with helical CT (-44 H) was more negative than with con-
ventional CT (-35 H) but not significantly so (p = .058). However, in the subset of patients
with masses that were 2 cm or less in diameter (n = 14), the mean attenuation values on heli-
cal CT were significantly lower than on conventional CT (-40 H versus -30 H, p < .05).
Likewise, for masses with attenuation values that differed by more than 6 H (ii = 8), when
imaged by the two techniques we again found that mean attenuation values on helical CT
were significantly lower (-43 H versus -24 H, p < .05).
CONCLUSION. Helical CT revealed angiomyolipoma across all cases as well as
conventional CT did. Also, helical CT was more sensitive in revealing fat in masses less
than 2 cm in diameter and in masses in which the attenuations of the two CT techniques
differed by a significant amount. We preferred helical CT over conventional CT when
examining small hyperechoic masses for the purpose of diagnosing angiomyolipoma.
Received February 28,1996; accepted after revision
April 15, 1996.
Presented at the annual meeting of the American
Roentgen Ray Society, Washington, DC, April-May 1995.
tAll authors: Department of Radiology. Brigham and
Women’s Hospital, Harvard Medical School, 75 Francis St.,
Boston, MA02115.Addresscorrespondenceto S.G. Silverman.
AJR 1996;167:877-881
0361-803X/96/1674-877
© American Roentgen Ray Society
M any small (3 cm) hyperechoic
. renal masses, often discovered
incidentally, represent angiomyo-
lipoma, a benign renal tumor consisting of
variable mixtures of blood vessels, smooth
muscle, and fat. However, two recent reports
suggest that the percentage of small renal can-
cers that are hyperechoic is greater than previ-
ously recognized. In one series, 61 % of small
renal cancers were hyperechoic [1]. A second
series reported that 32% of small renal can-
cers were markedly hyperechoic and mim-
icked angiomyolipomas [2]. These authors
recommended that all incidentally discovered
hyperechoic renal masses be further evaluated
with CT to confirm the presence of fat within
the mass, which is diagnostic of angiomyoli-
poma in most cases [2, 3].
CT is considered the most reliable test to
detect fat within small renal masses and thus
make the diagnosis of angiomyolipoma [3-5].
However, conventional CT may fail to reveal
the fat in small tumors or in tumors with small
amounts of fat [6]. Because of respiratory
misregistration (i.e., imaging at different
degrees of inspiration that results in skip areas
in the imaged organ or lesion), the portion of
the lesion containing fat or the entire lesion
could be missed. Helical CT eliminates respi-
ratory misregistration and has been shown to
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