Accepted Manuscript Metformin Induces Human Esophageal Carcinoma Cell Pyroptosis by Targeting the miR-497/PELP1 Axis Lu Wang, Kai Li, Xianjie Lin, Zhimeng Yao, Shuhong Wang, Xiao Xiong, Zhifeng Ning, Jing Wang, Xiaozheng Xu, Yi Jiang, Ditian Liu, Yuping Chen, Dianzheng Zhang, Hao Zhang PII: S0304-3835(19)30086-2 DOI: https://doi.org/10.1016/j.canlet.2019.02.014 Reference: CAN 14244 To appear in: Cancer Letters Received Date: 4 December 2018 Revised Date: 1 February 2019 Accepted Date: 8 February 2019 Please cite this article as: L. Wang, K. Li, X. Lin, Z. Yao, S. Wang, X. Xiong, Z. Ning, J. Wang, X. Xu, Y. Jiang, D. Liu, Y. Chen, D. Zhang, H. Zhang, Metformin Induces Human Esophageal Carcinoma Cell Pyroptosis by Targeting the miR-497/PELP1 Axis, Cancer Letters, https://doi.org/10.1016/ j.canlet.2019.02.014. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.