Journal Psychiatry and Cognitive Behaviour Research Article Ali Y, et al. J Psychiatry Cogn Behav 2: JPCB-105 Prevalence and Associated Factors of Antiepileptic Drug Non - De- partment of Dilla University Referral Hospital, Dilla, Gedeo, SN- NPR, Southern Ethiopia adherence among Epileptic Patients At- tending at out Patient 1 Volume 02; Issue 01 Maregu Shegaw, Reta kassa, Yigrem ali * , Negatu Addissu Department of Psychiatry, college of health sciences and Medicine, Dilla University, Ethiopia. Corresponding author: Yigrem ali, College of Health Sciences and Medicine, Dilla University, Ethiopia, Tel: + 251 463312462; E-mail: alyigrem@gmail.com Citation: Shegaw M, kassa R, Ali Y, Addissu N [2016] Prevalence And Associated Factors Of Antiepileptic Drug non - adherence Among Epileptic Patients Attending At Out Patient Departement Of Dilla University Referral Hospital, Dilla, Gedeo, SNNPR, Southern Ethiopia. J Psychiatry Cogn Behav 2: 105. DOI: 10.29011/2574-7762.000005 Received Date: 21 December, 2016; Accepted Date: 10 January, 2017; Published Date: 8 January, 2017 Abstract Background: Antiepileptic drugs are effective in the treatment of epilepsy, but poor adherence to medication is major problem to sustained remission and to functional restoration. Poor adherence to treatment is one of many reasons for pharmacological treatment failure and seizure recurrence. Even though there were studies on the magnitude and associ- ated factors of Antiepileptic drugs non-adherence, there is a shortage of published information regarding the prevalence and associated factors of Antiepileptic drugs none-adherence in Ethiopia. Objective: To assess prevalence and associated factors of antiepileptic drug none-adherence among epileptic patients attending at Dilla University Referral Hospital. Methods: Institutional based cross sectional study design was conducted at Dilla University Referral Hospital from March to May, 2016. A total of 265 individuals was selected by simple random sampling method and interviewed by using structured questionnaire 8-item Morisky Medication Adherence Scale was used to assess the prevalence of antiepi- leptic drug non adherence. Data was coded and exported to SPSS version 20 for analysis. Results: The prevalence of Antiepileptic’s drug none-adherence in this study was 38.1% and getting medication by payment [AOR=2.009,95%,CI:1.044,3.868], Patients who did not got health information about (their illness, duration of treatment and drug side effect], [AOR=0.319,95%,CI:0.184,0.534], poor social support [AOR=3.06, 95%, CI: 1.47- 6.37], skip dose [AOR=2.462,95%,CI:1.375,4.407], patients who were on treatment for 2-5 years [AOR=1.48, 95%, CI: 0.722,3.035] were found to be signifcantly associated (p<0.05). Conclusion: The prevalence of antiepileptic drug none-adherence among patients with epilepsy disorder was found 38.1%. Getting medication by payment, did not receive health information about [the illness, duration of treatment, medication side effect], skip dose, on treatment for 2-5 years, and poor social support were found to be the independent predictor of antiepileptic drug none-adherence. Key words: Antiepileptic Drugs; prevalence; epileptic pa- tients; Ethiopia Introduction Epilepsy is a chronic disorder of the brain and is one of the most common serious neurological disorders worldwide with no boundary to age, race, social class, nationality or geographical lo- cation [1]. Worldwide around One billion people are affected by neurological disorders, including 50 million who had epilepsy, 24 million with Alzheimer disease & other dementias, and an esti- mated 6.8 million die each year due to neurological disorders [2]. Among patients who had epilepsy; 85% of them found in devel- DOI: 10.29011/2574-7762.000005