ISPUB.COM The Internet Journal of Third World Medicine Volume 10 Number 1 1 of 5 Initial Data From The Intracranial Tumour Registry Of The University Of The West Indies: Radio-Pathological Correlation Of Meningiomas P Johnson, J Jaggon, C Bruce, J Campbell, I Crandon, G Char, D Eldemire- Shearer Citation P Johnson, J Jaggon, C Bruce, J Campbell, I Crandon, G Char, D Eldemire-Shearer. Initial Data From The Intracranial Tumour Registry Of The University Of The West Indies: Radio-Pathological Correlation Of Meningiomas. The Internet Journal of Third World Medicine. 2012 Volume 10 Number 1. Abstract INTRODUCTION: Meningiomas are the most common primary intracranial tumors. Despite the majority being benign, they can have a significant impact on morbidity and mortality due to mass effects. This paper seeks to utilize data from the newly instituted Intracranial Tumor Registry (ITR) at the University Hospital of the West Indies (UHWI) to report on the radio-pathologic correlation of meningiomas seen at that institution, the first in the region with the capability of performing such an analysis. METHOD: A review of all the cases entered in the ITR between the years 2006 and the present day was performed. Only patients with initial Magnetic Resonance Imaging (MRI) reports from the UHWI Radiology Department were included in this study, and these findings were correlated with the pathological findings from the surgical specimens reviewed at the UHWI. RESULTS: Of a total of 138 cases with imaging suggestive of meningioma, 85 had UHWI pre-operative imaging reports. 24 of these patients had a pathologic assessment and 18 (75%) were confirmed as meningioma, with demographic features in keeping with other studies. Of the remaining 6 patients, 4 had a malignancy diagnosed on histologic evaluation. CONCLUSION: Despite a relatively large number of patients undergoing imaging with a presumed diagnosis of meningioma, few (17%) had pathological confirmation; the major reasons for this are discussed. There was positive radio-pathologic correlation in 75% of the patients who had histologic appraisal of their intracranial lesions. This seems low in comparison to existing work regarding sensitivities and specificities of MRI in diagnosing meningioma. The actual images were not reviewed in this study. A further study reviewing the images involved in these cases may prove helpful. INTRODUCTION Meningiomas are primary intracranial tumors that arise from the arachnoid cap cells of the meninges. They are the most common primary intracranial tumors, and account for about 34% of all primary intracranial tumors (1). While the majority are benign, they have a significant impact on morbidity and mortality due to raised intracranial pressure and other results of mass effect. Data on meningiomas in Jamaica is scant. There has been one paper previously published describing the epidemiologic profile of meningiomas in Jamaica (2). There are, to date, no studies from the English speaking Caribbean documenting radio-pathological correlation. This paper seeks to utilize data from the newly instituted ITR to report the first such radio-pathological correlation from this region. METHOD A retrospective review of all the cases entered into the ITR was done using the search string “meningioma”. Only patients with initial MR imaging done at the UHWI were included in the study. The actual images were not reviewed. Pathological findings were retrieved from the files in the Pathology Department at the UHWI. The World Health Organization (WHO) 2007 criteria were employed for pathological grading. The following data was retrieved: A review of the radiological findings was performed, and a correlation with pathological findings was made. RESULTS 138 cases were initially identified from the ITR based on MRI reports suggesting a diagnosis of meningioma. Fifty-