Accepted Manuscript Title: Temporal Trends in the Clinical Acuity of Patients with ST-Segment Elevation Myocardial Infarction. Author: Udhay Krishnan, Josef A. Brejt, Joshua Schulman-Marcus, Rajesh V. Swaminathan, Dmitriy N. Feldman, Parag Goyal, S. Chiu Wong, Robert M. Minutello, Geoffrey Bergman, Harsimran Singh, Luke K. Kim PII: S0002-9343(17)30804-5 DOI: http://dx.doi.org/doi: 10.1016/j.amjmed.2017.06.040 Reference: AJM 14214 To appear in: The American Journal of Medicine Please cite this article as: Udhay Krishnan, Josef A. Brejt, Joshua Schulman-Marcus, Rajesh V. Swaminathan, Dmitriy N. Feldman, Parag Goyal, S. Chiu Wong, Robert M. Minutello, Geoffrey Bergman, Harsimran Singh, Luke K. Kim, Temporal Trends in the Clinical Acuity of Patients with ST-Segment Elevation Myocardial Infarction., The American Journal of Medicine (2017), http://dx.doi.org/doi: 10.1016/j.amjmed.2017.06.040. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.