TECHNICAL NOTE
J Neurosurg 127:139–147, 2017
H
emangioblastoma is a rare benign tumor of the
CNS that often occurs in the posterior fossa. Al-
though stereotactic radiosurgery has proven to be
effective in some cases,
6,9
microsurgical resection still re-
mains the gold-standard treatment option. Successful re-
section of the tumor depends on early interruption of the
arterial blood supply, frst of the feeding arteries and then
of the draining veins.
2,4,5,7,8
Therefore, the key to successful
treatment is to preoperatively assess the number of feed-
ing arteries, the courses of the feeding arteries, and the
point where the feeding arteries penetrate the tumor, thus
establishing the precise locations of the feeding arteries
in the actual operation feld.
19,22
Conventional angiography
is useful for the preoperative assessment,
10,17–19
provid-
ing precise information about the blood vessels, includ-
ing the feeding arteries and draining veins, but can give
little information about the tumor and surrounding brain
structures. Therefore, the exact relationship between these
vessels and the surrounding structures such as the tumor
and brainstem is diffcult to estimate. To estimate the pre-
cise locations of the feeding arteries in the actual operative
feld, simultaneous 3D visualization of the feeding arteries
and the surrounding structures is needed.
Three-dimensional multifusion medical imaging
(3DMMI) was recently reported to be useful in the com-
prehension of complicated anatomical relationships and
surgical simulations,
15,16,20,23
because this technique can si-
multaneously provide 3D information of multiple anatomi-
cal structures. However, even 3D medical imaging cannot
always identify the exact location of each feeding artery,
23
ABBREVIATIONS AICA = anterior inferior cerebellar artery; CTA = CT angiography; DSA = digital subtraction angiography; FIESTA = fast imaging employing steady-state
acquisition; hr-3DMMI = high-resolution 3D multifusion medical imaging; MRA = MR angiography; TOF = time of flight; TRICKS = time-resolved imaging of contrast kinetics;
3DRA = 3D rotated angiography.
SUBMITTED November 16, 2015. ACCEPTED May 27, 2016.
INCLUDE WHEN CITING Published online August 26, 2016; DOI: 10.3171/2016.5.JNS152646.
Usefulness of high-resolution 3D multifusion medical
imaging for preoperative planning in patients with
posterior fossa hemangioblastoma: technical note
Masanori Yoshino, MD, PhD,
1
Hirofumi Nakatomi, MD, PhD,
1
Taichi Kin, MD, PhD,
1
Toki Saito, PhD,
2
Naoyuki Shono, MD,
1
Seiji Nomura, MD,
1
Daichi Nakagawa, MD,
1
Shunsaku Takayanagi, MD, PhD,
1
Hideaki Imai, MD, PhD,
1
Hiroshi Oyama, MD, PhD,
2
and Nobuhito Saito, MD, PhD
1
Departments of
1
Neurosurgery and
2
Clinical Information Engineering, Graduate School of Medicine, The University of
Tokyo, Japan
Successful resection of hemangioblastoma depends on preoperative assessment of the precise locations of feeding
arteries and draining veins. Simultaneous 3D visualization of feeding arteries, draining veins, and surrounding structures
is needed. The present study evaluated the usefulness of high-resolution 3D multifusion medical imaging (hr-3DMMI)
for preoperative planning of hemangioblastoma. The hr-3DMMI combined MRI, MR angiography, thin-slice CT, and
3D rotated angiography. Surface rendering was mainly used for the creation of hr-3DMMI using multiple thresholds to
create 3D models, and processing took approximately 3–5 hours. This hr-3DMMI technique was used in 5 patients for
preoperative planning and the imaging fndings were compared with the operative fndings. Hr-3DMMI could simulate the
whole 3D tumor as a unique sphere and show the precise penetration points of both feeding arteries and draining veins
with the same spatial relationships as the original tumor. All feeding arteries and draining veins were found intraopera-
tively at the same position as estimated preoperatively, and were occluded as planned preoperatively. This hr-3DMMI
technique could demonstrate the precise locations of feeding arteries and draining veins preoperatively and estimate
the appropriate route for resection of the tumor. Hr-3DMMI is expected to be a very useful support tool for surgery of
hemangioblastoma.
https://thejns.org/doi/abs/10.3171/2016.5.JNS152646
KEY WORDS hemangioblastoma; high-resolution 3D multifusion medical imaging; technique; feeding artery; draining
vein; preoperative planning; oncology
©AANS, 2017 J Neurosurg Volume 127 • July 2017 139
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