214 ISSN: 2347-7881 PharmaTutor Magazine | Vol. 2, Issue 8 | magazine.pharmatutor.org Research Article In Vitro Evaluation of Antacid Potential of Curcuma Longa Linn DK Vir 1 *, Nandu Kayande 1 , Pankaj Kushwah 2 1 Department of Pharmacology, 2 Department of Pharmacognosy, Nimar Institute of Pharmacy, Dhamnod, Dhar, Madhya Pradesh, India *dkvir007@gmail.com ABSTRACT The study was aimed to evaluate the antacid properties of Curcuma Longa Linn rhizomes aqueous extract under simulated conditions. Fresh rhizome of Curcuma Longa Linn was homogenized and dried under shade and thus mass obtained was powdered, weighed and subjected for the evaluation of antacid profile of the drug antacid properties of Curcuma Longa Linn was evaluated using carbondioxide evolution method & Rossette Rice test. The Curcuma Longa Linn rhizome extract showed significant results for antacid effect (P < 0.05) at different doses and the results obtained were comparable to that of standard NaHCO 3 . The results of the present study suggest that extract of curcuma longa linn significantly neutralized acid and showed resistance against change in pH and also illustrate good antacid property The extract of curcuma longa linn, has shown to possess significant carminative and antacid property. Keywords: Antacid Potential, Curcuma Longa, In Vitro INTRODUCTION Use of plant products is increasing in many segment of the [1] population. At present; thousands of plant metabolites are being successfully used for the treatment of variety of diseases. According to an estimate, 80% of the world's population relied upon [2] plants for their medication. The use of the medicinal plants is increasing in many countries where 35% of drugs contain natural [3] products. Turmeric is one of most essential spices The human stomach secretes hydrochloric acid which is necessary for the digestion of food. When the stomach contains an excessive amount of hydrochloric acid, then the condition is called as hyperacidity or acid dyspepsia. Common symptoms associated with dyspepsia are typical feeling of restlessness, feeling of nausea, actual vomiting, sour belching with an aftertaste of the already-eaten food, stiffness in the stomach, which is called as anatomic dyspepsia, lack of desire for any other type of food indigestion constipation. Today, there are different types of medicines available to treat stomach acidity. They are categorized as either antacids, antihistaminic and proton pump inhibitor.Turmeric grows wild in the forests of South and Southeast Asia. It is one of the key ingredients in many Asian dishes. Tamil traditional medicine, called Siddha has recommended turmeric in food for its potential medicinal value, which is a topic of active research. Its use as a coloring agent is not of primary value in South Asian cuisine Curuma longa is widely used drug in herbal medicine It is used as a food coloring for curry and as a preservative for food along with used as anti inflammatory antibacterial agents wield verity of uses are found with use of turmeric Alzheimer's, Arthritis, Cancer and Diabetes How to cite this article: DK Vir, N Kayande, P Kushwah; In Vitro Evaluation of Antacid Potential of Curcuma Longa Linn; PharmaTutor; 2014; 2(8); 214-217