How to Cite: Nirmawati, K., & Rusli, M. (2022). Peritoneal tuberculosis with a clinical presentation similar to ovarian cancer: Case report. International Journal of Health Sciences, 6(S6), 11126–11132. https://doi.org/10.53730/ijhs.v6nS6.13055 International Journal of Health Sciences ISSN 2550-6978 E-ISSN 2550-696X © 2022. Manuscript submitted: 9 May 2022, Manuscript revised: 18 July 2022, Accepted for publication: 27 August 2022 11126 Peritoneal tuberculosis with a clinical presentation similar to ovarian cancer: Case report Kiki Nirmawati Department of Internal Medicine, Faculty of Medicine, Airlangga University – Dr. Soetomo General Hospital, Surabaya, East Java 60285, Indonesia *Corresponding author email: ned.indische.artsenschool@gmail.com Musofa Rusli Division of Infectious Diseases & Tropical Medicine, Department of Internal Medicine, Faculty of Medicine, Airlangga University – Dr. Soetomo General Hospital, Surabaya, East Java 60285, Indonesia Abstract---The approach to diagnosing peritoneal tuberculosis in patients is complex and often overlaps with other obstetric and gynecologic diseases. A 27-year-old woman with complaints of abdominal mass went to the DOTS clinic after surgical removal of an ovarian mass. Clinical, laboratory, and histopathological abdominal CT scans showed a picture of tuberculosis. The patient was then treated with a TB regimen and as a result his clinical condition improved and the mass shrank. Keywords---abdominal mass, ascites, peritonitial TB. Introduction Peritoneal tuberculosis is an inflammation of the parietal or visceral peritoneum caused by the bacterium Mycobacterium tuberculosis. This disease often affects the entire peritoneum and organs of the gastrointestinal system, mesentery, and internal genital organs. This disease rarely stands alone, usually is a continuation of the tuberculosis process in other places, especially the lungs. However, it is often found when the diagnosis is made, the tuberculosis process in the lungs is no longer visible. Clinical symptoms vary, generally complaints and symptoms arise slowly, often patients are not aware of this situation. The most common complaints are lack of appetite, cough, and fever. On physical examination, the most common symptoms are ascites, fever, abdominal swelling and pain, pallor and fatigue (Zain, 2014). Diagnosing abdominal TB remains a major challenge even for experienced clinicians. This disease is a great imitator that has an