Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/jdv.14909 This article is protected by copyright. All rights reserved. DR. RAHUL MAHAJAN (Orcid ID : 0000-0003-4320-3193) Article type : Letter to Editor Utility of whole exome sequencing in detecting novel compound heterozygous mutations in COL7A1 among families with severe recessive Dystrophic Epidermolysis Bullosa in India - implications on diagnosis, prognosis and prenatal testing Rahul Mahajan 1 , Shamsudheen Karuthedath Vellarikkal 2 , Sanjeev Handa 1 , Ankit Verma 2 , Rijith Jayarajan 2 , Anoop Kumar 2 , Dipankar De 1 , Jaswinder Kaur 3 , Inusha Panigrahi 4 , Vineeth VSl 5 Sridhar Sivasubbu 2,7 , Vinod Scaria 6,7 1 Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh 2 Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology, Delhi 3 Department of Obstetrics & Gynaecology,Postgraduate Institute of Medical Education and Research, Chandigarh 4 Department of Pediatric Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 5 Centre for DNA Fingerprinting and Diagnostics, 4-1-714, Tuljaguda Complex, Mozamzahi Road, Nampally, Hyderabad, Telangana 500001, India. 6 GN Ramachandran Knowledge Center for Genome Informatics, CSIR Institute of Genomics and Integrative Biology, Delhi 7 Academy of Scientific and Innovative Research (AcSIR), Delhi *Correspondence: Sridhar Sivasubbu. Email: s.sivasubbu@igib.res.in and Vinod Scaria. Email: vinods@igib.in Source(s) of support: Authors acknowledge funding for the work from the Council of Scientific and Industrial Research (CSIR), India through Grant No. BSC0212.The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.