www.wjpps.com │ Vol 12, Issue 6, 2023. │ ISO 9001:2015 Certified Journal │ 1270 Ali et al. World Journal of Pharmacy and Pharmaceutical Sciences GLYCEROL FATTY ACIDS DERIVATIVES FROM THE FRUITS OF LYCIUM CHINENSE MILLER Shahnaz Sultana 1,2 , Mohammed Ali 1 * and Showkat Rassol Mir 1 1 Phytopharmaceuticals Research Laboratory, School of Pharmaceutical Education and Research, Jamia Hamdard, P.O. Hamdard Nagar, New Delhi – 110062, India. 2 Present Address: College of Pharmacy, Jazan University, Jazan, Saudi Arabia. ABSTRACT The fruits of Lycium chinense Miller (Solanaceae) possess emmenagogue, diuretic, antipyretic and hepatoprotective properties and are used to stimulate the immune system, to increase hormonal growth, to improve blood circulation and eye sight and to cure morning sickness. Phytochemical investigation of a chloroform extract of the fruits afforded four fatty acid glycerides identified as 1-linolenio-2- linoleio-3-palmitoyl glyceride (1), 1,3-dilinoleio-2-oleoglyceride (2), 1,3- dioleo-2-linolenioglyceride (3) and 1-linolenio-2-oleo-3-arachidyl glyceride (4). The structures of these phytoconstituents have been elucidated on the basis of spectral data analysis. KEYWORDS: Lycium chinense, Fruits, Fatty acid glycerides, Isolation, Structure elucidation. INTRODUCTION Lycium chinense Miller (family Solanaceae), known as Goji berry or Gou-qu-zi, is a cold- hard, perennial, sprawling, nearly prostrate shrub, bark brown-red, fruits bright red. Its origin is believed to be in the region of south-eastern Europe and south-western Asia, but now it is cultivated throughout the world. Today China is the largest producer of this fruit. The young leaves are eaten as a vegetable, and the seed oil is used as a lubricant and for cooking, the species also grown for controlling erosion. [1] The dried fruits are emmenagogue, diuretic, antipyretic, tonic and hepatoprotective and marketed in Ayurvedic and herbal health shops as the Tibetan or Himalayan Goji berry. The red-orange ellipsoid fruits stimulate the WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES SJIF Impact Factor 7.632 Volume 12, Issue 6, 1270-1280 Research Article ISSN 2278 – 4357 *Corresponding Author Dr. Mohammed Ali Phytopharmaceuticals Research Laboratory, School of Pharmaceutical Education and Research, Jamia Hamdard, P.O. Hamdard Nagar, New Delhi – 110062, India. Article Received on 28 March 2023, Revised on 18 April 2023, Accepted on 08 May 2023 DOI: 10.20959/wjpps20236-24923