Treatment of a Basilar Trunk Perforator Aneurysm
With the Pipeline Embolization Device:
Case Report
BACKGROUND AND IMPORTANCE: Basilar trunk perforator (BTP) aneurysms are rare
lesions that pose significant challenges to microsurgical clipping and endovascular
coiling. We present the intriguing case of a ruptured BTP aneurysm that was success-
fully treated with the Pipeline Embolization Device (PED).
CLINICAL PRESENTATION: An elderly woman presenting with subarachnoid hemor-
rhage was found to have a 1.5-mm aneurysm arising from the proximal portion of a thin
midbasilar perforator. The decision was made to treat this aneurysm with flow diversion
in an attempt to preserve the patency of the perforator and to avoid the hazards
associated with parent vessel trapping. A 3 · 12-mm PED was successfully deployed in
the basilar trunk across the neck of the aneurysm, causing stasis in the aneurysm, with
continuous flow through the parent vessel. The procedure and postoperative course
were uneventful. A follow-up angiogram 2 weeks later showed complete disappearance
of the aneurysm with preservation of the patency of the perforator. At the 6-month
follow-up, the patient was asymptomatic and remained neurologically intact.
CONCLUSION: We present the first case of a BTP aneurysm treated with the PED. The
aneurysm was successfully occluded, and the patency of the feeding vessel was pre-
served. In light of the limitations of coiling and the hazards associated with microsur-
gery and parent vessel trapping, the PED may be a valuable option for BTP aneurysms.
KEY WORDS: Aneurysm, Basilar perforator, Flow diversion, Pipeline Embolization Device
Neurosurgery 74:E697–E701, 2014 DOI: 10.1227/NEU.0000000000000308 www.neurosurgery-online.com
B
asilar trunk perforator (BTP) aneurysms
are rare lesions that present with subarach-
noid hemorrhage (SAH), usually perime-
sencephalic in pattern.
1,2
It is a formidable
challenge for the neurosurgeon to treat these
lesions with either microsurgery or traditional
embolization strategies.
Flow diversion has emerged as a promising
treatment strategy for several types of aneurysms at
various intracranial locations.
3-10
The Pipeline
Embolization Device (PED; eV3, Irvine, California)
is a dedicated flow diverter that received US Food
and Drug Administration approval in 2011 for
large and giant wide-necked aneurysms arising
from the cavernous segment to the superior
hypophyseal segment of the internal carotid
artery. We present the intriguing case of a rup-
tured BTP aneurysm that was successfully treated
with the PED. This is the first description of
a BTP aneurysm treated with a flow diverter.
CLINICAL PRESENTATION
An elderly woman presented to an outside
institution with the worst headache of her life. A
head computed tomography showed extensive SAH
predominantly in the basal cisterns with some
associated intraventricular hemorrhage (Figure 1).
A computed tomographic angiography showed
a questionable tiny aneurysm adjacent to the basilar
trunk (Figure 2). The patient was transferred to our
institution for further evaluation and management.
On admission, the patient was noted to be
neurologically intact. An angiogram performed on
post-SAH day 1 failed to identify a clear aneurysm
but showed a blush of contrast next to the basilar
trunk. The patient was taken for a second angiogram
Nohra Chalouhi, MD
Pascal Jabbour, MD
Robert M. Starke, MD
Mario Zanaty, MD
Stavropoula Tjoumakaris, MD
Robert H. Rosenwasser, MD
L. Fernando Gonzalez, MD
Department of Neurosurgery, Thomas
Jefferson University and Jefferson Hos-
pital for Neuroscience, Philadelphia,
Pennsylvania
Correspondence:
L Fernando Gonzalez, MD,
Associate Professor,
Department of Neurological Surgery,
Division of Neurovascular Surgery and
Endovascular Neurosurgery,
Thomas Jefferson University Hospital,
901 Walnut St, 3rd Floor,
Philadelphia, PA 19107.
E-mail: fernando.gonzalez@jefferson.edu
Received, December 16, 2013.
Accepted, January 20, 2014.
Published Online, January 31, 2014.
Copyright © 2014 by the
Congress of Neurological Surgeons.
ABBREVIATIONS: BTP, basilar trunk perforator;
PED, Pipeline Embolization Device
CASE REPORT
TOPIC CASE REPORT
NEUROSURGERY VOLUME 74 | NUMBER 6 | JUNE 2014 | E697
Copyright © Congress of Neurological Surgeons. Unauthorized reproduction of this article is prohibited.