2023, March Edition |www.jbino.com | Innovative Association J.Bio.Innov12(2), pp: 276-285, 2023 |ISSN 2277-8330 (Electronic) Obeagu et al., https://doi.org/10.46344/JBINO.2023.v12i02.06 PREVALENCE OF RHESUS C AND Du PHENOTYPES AMONG PREGNANT WOMEN ATTENDING ANTENATAL CLINIC AT BOWEN UNIVERSITY TEACHING HOSPITAL (BUTH) OGBOMOSO, NIGERIA Arinze Favour Anyiam 1 , Ejeatuluchukwu Obi 2 , Onyinye Cecilia Arinze-Anyiam 1 , Emmanuel Anyachukwu Irondi 3 , Pius Omoruyi Omosigho 4 , Musa Abidemi Muhibi 4 , Ayodele Ilesanmi 5 , Akintola Ayodeji Stella 5 , Blessing Okezie 6 and *Emmanuel Ifeanyi Obeagu 7 1 Department of Medical Laboratory Science, Haematology Unit, Faculty of Basic Medical and Health Sciences, Thomas Adewumi University, Oko, P. M. B. 1030, Kwara State, Nigeria. 2 Toxicology Unit, Department of Pharmacology and Therapeutics, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Anambra State, Nigeria 3 Department of Medical Biochemistry and Pharmacology, Faculty of Pure and Applied Sciences, Kwara State University, Malete, P.M. B. 1530, Kwara State, Nigeria. 4 Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, Edo State University, Uzairue, Edo State, Nigeria. 5 Department of Medical Laboratory Science,, Faculty of Pure and Applied Sciences, Kwara State University, Malete, P.M. B. 1530, Kwara State, Nigeria. 6 Department of Medical Laboratory Science, Achiever’s University, Owo, Ondo State, Nigeria. 7 Department of Medical Laboratory Science, Kampala International University, Uganda. ABSTRACT The aim is this study is to determine the prevalence of Rh c and Du phenotype among pregnant women attending antenatal clinic (ANC) in Bowen University Teaching Hospital Ogbomoso. The prevalence and distribution of Rh C and Du phenotype was determined using 50 blood samples of 50 different pregnant women consecutively recruited pregnant women aged 18-40 years. Samples were tested for Rh C and Du phenotype using the conventional tube agglutination method using Rapid Laboratories (UK) anti C and Du antisera. Out of 50 samples studied, the prevalence of Rh C was 28% (positivity) while Rh Du was 92% (positivity). The prevalence of Rhesus Du antigens was higher in Ogbomoso since 46 out of 50 samples (92%) tested positive for Rhesus Du antigens. In addition, a 28% prevalence (positivity) obtained does not postulate that Rhesus C antigen distribution in pregnant women in Ogbomoso is low. We recommend that all pregnant women in the area be screened for the presence of clinically significant red cell antigens including Rh C and Du blood group antigens on their first antenatal visit. Keywords: prevalence, rhesus C, Du phenotypes, pregnant women