Crit Care Nurs Q Vol. 41, No. 2, pp. 161–169 Copyright c  2018 Wolters Kluwer Health, Inc. All rights reserved. Effects of Nurse-Led Intervention on Patients’ Anxiety and Sleep Before Coronary Artery Bypass Grafting Nesa Mousavi Malek; Masoumeh Zakerimoghadam; Maryam Esmaeili; Anoushiravan Kazemnejad The aim of this study to examine the effects of supportive-educational nurse-led intervention on the patients’ anxiety and sleep before the coronary artery bypass grafting. The current clinical trial recruited 160 patients (N = 160) waiting for the coronary artery bypass grafting by random block sampling and divided them into two 80-people experimental and control groups. Spielberger’s State Anxiety Inventory was completed on the first day. The Groningen’s Sleep Quality Index was also completed by the patients on the day of surgery. Data were analyzed in SPSS software version 16, using descriptive and inferential statistics tests. The mean anxiety score in the experimental group decreased to 48.39, whereas in the control group, the mean anxiety score saw a rise after the intervention (61.09). The comparison of the mean quality of sleep the night before the surgery for both groups showed that sleep in the control group compared with sleep in the experimental group had a lower quality, and statistically, it was significant (P < .001). Results showed that non- pharmacological and supportive interventions can reduce patients’ anxiety and sleep disturbance before the coronary artery bypass grafting. According to the results, nonpharmacological thera- pies should be placed at the top of nurses’ tasks. Key words: anxiety, coronary artery bypass grafting, nursing, sleep Author Affiliations: School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran (Mss Mousavi Malek and Zakerimoghadam); School of Nursing and Midwifery, Nursing and Midwifery Care Research Center, Tehran University of Medical Sciences, Tehran, Iran (Ms Esmaeili); and Department of Biostatics, Tarbiat Modares University, Tehran, Iran (Mr Kazemnejad). The authors thank all of participants during the differ- ent stages of this study. This study was one part of a master of science thesis of the first author, financially supported by Tehran University of Medical Sciences. This article was derived from a student thesis from Tehran University of Medical Sciences, approved by the ethics committee of the university (142232, Decem- ber 7, 2014), and registered at Iranian clinical trial site (IRCT201406154443N1). The authors thank the respectable professors of the School of Nursing and Midwifery, Tehran University of Medical Sciences, and nurses in the CCU and cardiac surgery units of the hos- pitals and all the patients attending this research. All authors have made an active contribution to the conception, design, analysis, and interpretation of the data of the article, and all have critically reviewed con- tent of the article. All authors have approved the fi- nal version submitted for publication, and all authors agree to the submission of the manuscript to the jour- nal. All authors declare that they have no competing interests. This research received funding from Tehran University of Medical Sciences. This research project has been approved by a research ethics committee of the Tehran University of Medical Sciences (TUMS). No conflict of interest has been declared by the authors. Correspondence: Masoumeh Zakerimoghadam, School of Nursing and Midwifery, Tehran University of Medical Sciences, Nosrat St, Tohid Sq, Tehran, Iran (zakerimo@tums.ac.ir). DOI: 10.1097/CNQ.0000000000000195 Copyright © 2018 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited. 161