A Comprehensive System
for Identifying Patients
With Type 1 Diabetes at
Increased Risk for
Diabetic Ketoacidosis at
Texas Children’s Hospital
David D. Schwartz,
1
Mili Vakharia,
2
Serife Uysal,
2
Kristen R. Hendrix,
2,3
Kelly Fegan-Bohm,
2
Sarah K. Lyons,
2
Rona Sonabend,
2
Sheila K. Gunn,
2
Rosa Banuelos,
4
and Selorm Dei-Tutu
2
Quality Improvement Success Stories are published by
the American Diabetes Association in collaboration with
the American College of Physicians and the National Dia-
betes Education Program. This series is intended to high-
light best practices and strategies from programs and
clinics that have successfully improved the quality of
care for people with diabetes or related conditions. Each
article in the series is reviewed and follows a standard
format developed by the editors of Clinical Diabetes. The
following article describes a project at Texas Children’s
Hospital aimed at improving identification of patients
with type 1 diabetes at high risk for diabetic ketoacidosis.
Describe your practice setting and location.
Texas Children’s Hospital, located in Houston, TX, is the
largest pediatric hospital in the United States, with 973
inpatient beds and extensive outpatient clinics and serv-
ices. It is the primary pediatric teaching hospital of
Baylor College of Medicine. The Texas Children’s Endo-
crine and Diabetes Care Center is one of the largest
pediatric endocrinology and diabetes centers in the
country, with three inpatient facilities and seven ambu-
latory clinics. The service is staffed by a multidisciplin-
ary team that includes endocrinologists, endocrine
fellows, advanced practice providers, certified diabetes
care and education specialists (CDCESs), dietitians,
social workers, and consulting psychologists. Almost
500 youth with newly diagnosed type 1 diabetes are
admitted to the hospital each year, with a total pediatric
diabetes population of >3,400 patients.
Describe the specific quality gap addressed
through the initiative.
Diabetic ketoacidosis (DKA) is an acute, severe, and
preventable complication of diabetes that can result in
significant morbidity and mortality. The most common
cause of DKA in children and adolescents with estab-
lished type 1 diabetes is inadvertent or deliberate insu-
lin omission, often occurring in the context of
chronically poor glycemic control. Identifying risk fac-
tors for diabetes-related morbidities is crucial to inform
preventive efforts and target services to the patients in
greatest need, with the ultimate goal of reducing the
incidence of DKA.
Before the start of this project, our hospital had no
structured, formal way to identify patients with type 1
diabetes at greatest risk for poor glycemic control and
DKA. Patients considered high risk might have been
referred to social work or psychology staff by their dia-
betes care providers, but this was a hit-or-miss process,
with many patients likely being missed. More com-
monly, patients would only be referred after experienc-
ing one or more episodes of DKA. The care of these
patients was therefore mostly reactive, resulting in
increased morbidity and hospitalizations and incurring
significant expense. To reduce complications and
1
Section of Psychology, Department of Pediatrics, Baylor College of Medicine, Houston, TX;
2
Section of Pediatric Diabetes and Endocrinology,
Department of Pediatrics, Baylor College of Medicine, Houston, TX;
3
Piedmont Physicians Endocrinology, Columbus, GA;
4
Texas Children’s
Hospital Quality Outcomes and Analytics, Houston, TX
Corresponding author: David D. Schwartz, ddschwar@bcm.edu
This series is published by the American Diabetes Association in collaboration with the American College of Physicians, Inc., and the
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This article contains supplementary material online at https://doi.org/10.2337/figshare.16776247
https://doi.org/10.2337/cd21-0072
©2022 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational
and not for profit, and the work is not altered. More information is available at https://diabetesjournals.org/journals/pages/license.
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QUALITY IMPROVEMENT SUCCESS STORY
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