CONCLUSIONS: Type 2 D.M is significantly associated with lower serum PSA, Testosterone and larger prostate volume. Source of Funding: none MP13-15 THE RELATIONSHIP BETWEEN SLEEP DISORDERS AND LOWER URINARY TRACT SYMPTOMS: RESULTS FROM THE NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY (NHANES) Richard Fantus*, Chicago, IL; Brian Helfand, Chi-Hsiung Wang, Evanston, IL INTRODUCTION AND OBJECTIVES: It has been demon- strated that sleep disorders (SDOs) are associated with the prevalence of nocturia in men. While previous literature supports that patients with obstructive sleep apnea (OSA), insomnia, and restless leg syndrome (RLS) are at increased risk of nocturia, the risk of daytime lower urinary tract symptoms (LUTS) in these groups has not been established. We sought to investigate the frequency of LUTS in men with and without different types of SDO. METHODS: We examined the National Health and Nutrition Examination Survey (NHANES) database between 2006-2008. Men age 18-70 years who completed the sleep questionnaires in addition to the prostate and kidney forms were included in the study. LUTS was defined as having one more of the following symptoms: hesitancy, incomplete emptying, or nocturia (>¼2). Physician-diagnosed SDOs were self reported by patients. Statistical analyses were used to compare groups of men with and without a SDO. RESULTS: Of the 6185 men who completed all of the survey questions, 437 (7.1%) men reported a SDO. The clinical character- istics of men with and without a SDO are shown in Table 1. Men with SDOs were significantly older and significantly more likely to be Caucasian, have increased BMI and report more medical co-mor- bidities compared to men without SDOs. There was a significantly higher proportion of men with SDOs who reported nocturia compared to those without SDOs (39% vs 27.7%; p <.0001). Additionally, these men had a significantly higher risk of LUTS (including daytime LUTS) than men without SDOs (34.4% vs 22.8%, p <.0001). Men with OSA (31.7%) were significantly more likely to report >¼2 LUTS compared to men with insomnia (18.2%) or RLS (12.5%) (p¼.0002). CONCLUSIONS: Older age, Caucasian race, elevated BMI, and increased comorbidity score appear to be associated with an increased risk of LUTS in men with SDOs. While men with SDOs report increased nocturia, they are also more likely to experience bothersome daytime LUTS. This is particularly relevant for men with OSA compared to other SDOs. Based upon the present data, clinicians should consider assessing LUTS in men with SDOs as intervention could improve both nighttime and daytime urinary symptoms. Source of Funding: NorthShore University Health System MP13-16 FACTORS THAT PREDISPOSE TO LOWER URINARY TRACT SYMPTOMS IN DIABETIC MEN: RESULTS FROM THE NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY (NHANES) Richard Fantus*, Chicago, IL; Brian Helfand, Chi-Hsiung Wang, Evanston, IL; Brad Erickson, Iowa City, IA INTRODUCTION AND OBJECTIVES: It has been well estab- lished that diabetes mellitus (DM) is a significant risk factor for lower urinary tract symptoms (LUTS). However, data suggests that only approximately 50% of diabetics report bothersome LUTS. We sought to investigate the clinical characteristics that contribute to LUTS in men with diabetes. METHODS: The 2001-2008 National Health and Nutrition Examination Survey (NHANES) database was examined. The records of men age 18-70 years who completed the diabetes form in addition to the prostate and kidney forms were analyzed. LUTS was defined as having one or more of the following symptoms: hesitancy, incomplete emptying, or nocturia >¼2). Patients’ diabetes status, clinical charac- teristics and laboratory values were recorded. Statistical analyses was used to compare the frequency of clinical variables among diabetics with and without LUTS. RESULTS: 19202 patients met inclusion criteria including 1157 (6%) with DM. DM patients were significantly more likely to report hesitancy (12.2% vs 9.5%, p¼0.012), nocturia (50.1% vs 25.4%, p<.001) but not incomplete emptying (83.6% vs 86.5%, p¼.024) compared to non-DM patients. Diabetic men with LUTS were significantly older (63.5 vs 57.5 years, p<.001), more likely to be Caucasian (45.5% vs 28.2%, p¼0.002) and more likely to report more medical co-morbidities (32% vs 29.1%, p¼<.001) compared to non-DM patients without LUTS. Insulin did not alter the frequency of LUTS among DM patients (p>.05). Diabetic men with retinopathy were significantly more likely to report urinary hesitancy (38.9% vs 21.8%, p<.001), but significantly less likely to report incomplete emptying (21.9% vs 78.1%, p¼.004) and >¼2 different LUTS (23.1% Vol. 197, No. 4S, Supplement, Friday, May 12, 2017 THE JOURNAL OF UROLOGY â e159