Raghavendra Rao M.V INTERNATIONAL JOURNAL OF CURRENT MEDICAL AND PHARMACEUTICAL RESEARCH ISSN: 2395-6429, Impact Factor: 4.656 Available Online at www.journalcmpr.com Volume 8; Issue 07(A); July 2022; Page No.321-325 DOI: http://dx.doi.org/10.24327/23956429.ijcmpr20220074 Research Article A CITATION, DISTINCTION, HONOR, AND TRIBUTE, TO FRONTLINE CORONA WARRIORS Raghavendra Rao M.V 1 , Vijay Kumar Chennamchetty 2 , MM Karindas 3 , Ilie Vasiliev 4 , Hitesh Lakshmi Billa 5 , Mahendra Kumar Verma 6 and Manickdass 7 1 Department of Medicine, Apollo Institute of Medical Sciences and Research, Jubilee Hills, Hyderabad, Telangana, India 2 Department of Pulmonary Medicine, Apollo Institute of Medical Science and Research, Hyderabad, TS, India 3 Department of Oncology, World Academy of Medical Sciences, Netherlands 4 Department of Internal Medicine, World Academy of Medical Sciences, Netherlands 5 Interventional Pulmonology, Apollo Institute of Medical Science and Research, Hyderabad, TS, India 6 Department of Basic Sciences, American University School of Medicine, Aruba, Caribbean islands, Netherlands Antilles 7 Department of Microbiology, Apollo Institute of Medical Science and Research, Hyderabad, TS, India ARTICLE INFO ABSTRACT 2020 was a healthdevastating year. Pandemics do not die-they fade away.COVID-19 disease appears to have been associated with significant mortality amongst doctors and health care workers globally. The forfeit that they are making for the safety and welfare of human is invaluable. The frontline warriors like the doctors, Health Department officials, tahsildars, executive officers etc., have been working relentlessly to save lives, thereby keeping the death rate at the lowest. 'Death and grief has made us numb. The sleep-abated champions encompasses doctors, nurses, medical cleaners, pathologists, paramedics, ambulance drivers, and health-care administrators. Copyright © 2022 Raghavendra Rao M.V et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. INTRODUCTION COVID-19 is correlated with an acute respiratory distress syndrome (ARDS) and severe pneumonia (1) origin of this virus, SARS-CoV-2 probably arises from a natural selection in the animal host or a selection in humans (2) This virus is preferred in cells of the respiratory tract, epithelial hair cells of the airways and type 2 alveolar pneumocytes in SARS-CoV infections [3] “It makes no difference whether you get infected and then vaccinated, or if you get vaccinated and then a breakthrough infection,” said FikaduTafess, co-author of the study. “In either case, you will get a really, really robust immune response — amazingly high (4)After two years of a pandemic that has seen nearly 500 million people infected and billions vaccinated, the studies highlighted the importance of getting jabbed for those who have natural immunity after recovering from the disease (5) COVID-19 disease, may lead to respiratory failure and mechanical ventilation (6) Respiratory failure with mechanical ventilation need was reported in 2.3% up to 33% of the affected patients (7,8) Recently, however, autopsy studies have been published from throughout the world that have defined diffuse alveolar damage (DAD) as the histopathologic hallmark of severe SARS-CoV-2 infection (9) Identifying co-infections of more than one respiratory virus can help with understanding the various clinical symptoms, long-lasting effects on health, and appropriate methods of prevention (10) As of April 11, 2020, a total of 20,043 people died due to the COVID-19 pandemic outbreak in America, while approximately 521,084 cases have been registered in the national healthcare system(11) The novel Coronavirus SARS- CoV-2 outbreak has created a significant impact on the daily life and health care systems across the world including India (12,13) Article History: Received 06 th April, 2022 Received in revised form 14 th May, 2022 Accepted 23 rd June, 2022 Published online 28 th July, 2022 Key words: COVID-19, Coronavirus, Pandemics, Physicians, Health personnel, Health care, Mortality,