Accepted Manuscript Discovery and structure-activity relationship of auriculatone: a potent hepato- protective agent against acetaminophen-induced liver injury Meng Zhou, Min Wang, Rui-Feng Zhong, Xiang-Ming Liao, Lian-Li Deng, Guo-Bo Xu, Xun He, Jing Li, Yong-Jun Li, Ting Liu, Yong-Lin Wang, Shang- Gao Liao PII: S0960-894X(17)30724-2 DOI: http://dx.doi.org/10.1016/j.bmcl.2017.07.028 Reference: BMCL 25141 To appear in: Bioorganic & Medicinal Chemistry Letters Received Date: 23 February 2017 Revised Date: 16 June 2017 Accepted Date: 8 July 2017 Please cite this article as: Zhou, M., Wang, M., Zhong, R-F., Liao, X-M., Deng, L-L., Xu, G-B., He, X., Li, J., Li, Y-J., Liu, T., Wang, Y-L., Liao, S-G., Discovery and structure-activity relationship of auriculatone: a potent hepatoprotective agent against acetaminophen-induced liver injury, Bioorganic & Medicinal Chemistry Letters (2017), doi: http://dx.doi.org/10.1016/j.bmcl.2017.07.028 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.