Volume 8, Issue 1, January – 2023 International Journal of Innovative Science and Research Technology ISSN No:-2456-2165 IJISRT23JAN099 www.ijisrt.com 516 An Overview of Gulma and its Relation to Gallbladder Cancer Dr. Priyanka Katru * , Dr. Renu Sharma * , Dr. Sharad Porte ** ,. Anita Sharma *** * PhD Scholar, Department of Agad Tantra, NIA- Jaipur, Rajasthan- India ** Associate Professor, Department of Agad Tantra, NIA- Jaipur, Rajasthan- India *** Professor and HOD, Department of Agad Tantra, NIA- Jaipur, Rajasthan- India Corresponding author: Dr. Priyanka katru, BAMS, MD (Ayu), PhD scholar, Department of Agad tantra, NIA- Jaipur, Rajasthan- India Abstract:- Background: Gulma is one of the eight diseases elaborately described by Acharya Charaka in Nidaan sthana. It includes a wide spectrum of gastrointestinal and gynaecological illnesses with clinical signs and symptoms such as pain, swelling, lumps and tumours. Aims and objectives: This article makes an attempt to analytically correlate the disease with current day diagnosed and confirmed GBC or Abdominal tumours in general Material and methods: Classical Ayurvedic books, particularly the Charaka Samhita, were thoroughly reviewed, along with Sanskrit commentary, to acquire pertinent references and achieve depth in the notion. A thorough search of the topic was undertaken using the keywords Gulma, Charaka Samhita, Prakriti Sama Samaveta, Vikriti Vishama Samaveta, Trishothiya adhyaya, Phantom tumours, and Cancer, on the search engines Google, Bing, Pub Med, and AYUSH Portal, NAMASTE portal. Furthermore, key points were selected from several text books and published power point presentations. Discussion and conclusion: Though the term cancer is new to Ayurveda, Arbuda and gulma are names that denote malignant tumours. Various references of brihtryi and laghutryi demonstrate the relationship of gallbladder cancer to gulma, whether it is its anatomical position, clinical manifestation, or dosha dushya involvement. Keywords:- Gulma, phantom tumour, Gallbladder cancer, Ayurveda, arbuda. I. INTRODUCTION Gulma is a clinical condition with a very complicated clinical presentation. It is only compared to an abdominal lump or uterine fibroids, which is neither accurate nor appropriate. A "gulma" is a clump of trees, a thicket, a bush, or a shrub. 1 The word appears and has the same meaning in a variety of Ancient historical philosophy. 2 Many Ayurvedic drugs and diseases have remained elusive since its inception. Some medications are disputed, while others are not classified at all. Similarly, when it comes to diagnosis, certain illnesses are unknown or are viewed differently by different physicians. This could be attributed to Guru Shishya Parampara's dissemination of the method as well as the lack of a written description. The disciples interpret the same explanation differently, as is natural. With this uncertainty, certain diseases, such as Gulma, became only of academic interest over time. This disease is defined differently by different authors; the most common term is Phantom tumour, a broad term that can be interpreted and diagnosed in a patient by other physicians in a variety of ways. Gulma is a mass of dosha (bodily humours) in ayurvedic texts, specifically Vata Dosha, collected in a dense, almost rounded, bubble-like mass. It could be in a multiple simultaneous group, and it can move freely inside the cavity of its growth or not. 3 When Gulma gets too thick, it also appears that its overlapping muscles and skin are high, as though they were not inspected. 4 Gulma has been described in Ayurveda as large palpable, altered, intra-stomach swellings between the Hridaya (upper mid-region) and the Basti (bladder) regions, which develop as a result of Dosha accumulation with Vata transcendence. Such nodes are either transient or static and exhibit the characteristics of unrestrained rebound and return. Gulma is usually non-suppurative swellings separated from other intra- stomach nodes, such as Antarvidradhi (internal abscesses), where decay is normal. 5  Aims and Objectives This article makes an attempt to analytically correlate the disease with current day diagnosed and confirmed GBC or Abdominal tumours in general. II. MATERIALS AND METHODS Classical Ayurvedic texts, particularly the Charaka Samhita, were meticulously surveyed, along with Sanskrit commentaries, to gather relevant references and achieve depth in the concept. A thorough search of the topic was conducted using the keywords Gulma, Charaka Samhita, Prakriti Sama Samaveta, Vikriti Vishama Samaveta, Trishothiya adhyaya, Phantom tumours and Cancer, among others, on the search engines Google, Bing, Pub Med, and AYUSH Portal, NAMASTE portal. In addition, important points were extracted from various text books and published power point presentations.