Indian Journal of Forensic Medicine & Toxicology, January-March 2021, Vol. 15, No. 1 1991 Demographic and Clinicohistological Profles of Women Diagnosed with Breast Cancer at Al-El Wiya Maternity Teaching Hospital / Baghdad: A Retrospective Study Zaynab S. Abdulghany 1* , Najim Al-Kalidy 2 , Maeda H. Mohammad 1 , Noor H. Ismail 1 1 Lecturer, Iraqi Center For Cancer And Medical Genetics Research / Mustansiriyah University / Baghdad /Iraq, 2 Consultant General Surgeon Women tumor center at Al-El Wiya maternity teaching hospital/Baghdad / Iraq Abstract Knowing the incidence of, breast cancer, diagnosis, and treatment methods given a strategic approach for community awareness and rapid management. This study was aimed to: Estimate the demographic pattern including age, marital status, number of children, mass location, lactation, using contraceptive and smoking habit and to estimate the pattern of BC risk factors including family history, histological type, grading, and staging. The retrospective cross-sectional descriptive design was utilized. A total of 282 confrmed breast cancer female patients for the years 2016 to 2018 were included. Overall result showed that the age of Breast cancer female patients ranged from (25-80) years with a mean (49.12±0.67). Most Breast Cancer cases were diagnosed with infltrating ductal carcinoma (73.4%). The percentage of the discovered tumor was dominating the right side of the breast (52.8%). Also, 11% of BC females were diagnosed with stage IIa. And 31.2 % of BC cases were diagnosed as grade II. However, 20.2% of the cases were having a family history with breast cancer. Most of the cases (94.7%) were did not checked for biomarker testing, just 12 cases (4.3%) were positive ER. And 3.9% of cases tested for PR only 11 cases were positive. While negative results for HER2/neu was only in 9 cases (3.2%). Current study validates scientifc knowledge about BC in Baghdad. Each year, the incidence rates increase especially for age above 49. Keywords: Iraqi breast cancer, awareness, early detection, biomarkers, retrospective, ductal carcinoma Corresponding author: Zaynab S. Abdulghany Lecturer, Iraqi center for cancer and medical genetics research / Mustansiriyah University. Email: zaynab.saad@iccmgr.org Introduction Cancer incidence looks like a scale of diatonic, the increasing faced by increasing in society age and unhealthy lifestyles and premature death that would reduce the country’s productivity. According to data published by the Globocan site that in the 2030 year about 13 million people may die from cancer incidence worldwide, three-quarter of them may be in low income and middle-income countries (1) . The breast cancer new cases increasing gradually and stand at the top frst rank among other cancer in Iraq depending to the Annual report of the Iraqi cancer registry and this affected the community population (2) . The Iraqi national program for early detection of breast cancer, which was initiated since 2001, in an attempt to down-stage this disease at the time of presentation. Since then, specialized centers and clinics for early detection of breast tumors have been established in the major hospitals in all Iraqi provinces. Most screening and biological detection techniques simplify the early diagnosis of breast cancer; immunohistochemistry for biomarkers detection (2) , ELISA for blood assay analysis (3) , and the golden standard method is the presence of screening programs using mammography as an imaging technique (4,5) . Still, self-breast screening is the major easy early detection method (5) . All these techniques were present in the Iraq strategy of screening programs. The innovation of several genetic factors has been found to detect breast cancer for example; BRCA1 and BRCA2 were the most important tests, followed by MYC and P53. These tests are available, more specifc