Continence outcomes of robot-assisted radical
prostatectomy in patients with adverse urinary
continence risk factors
Anup Kumar, Srinivas Samavedi, Anthony S. Bates, Rafael F. Coelho, Bernardo Rocco,
Kenneth Palmer and Vipul R. Patel
Department of Urology, University of Central Florida College of Medicine and Global Robotics Institute, Florida Hospital-
Celebration Health, Celebration, FL, USA
Presentation at international meeting: European Association of Urology Annual Scientific Meeting 2014, Stockholm.
Objective
To analyse the continence outcomes of robot-assisted radical
prostatectomy (RARP) in suboptimal patients that have
challenging continence recovery factors such as enlarged
prostates, elderly patients, higher body mass index (BMI),
salvage prostatectomy, and bladder neck procedures before
RARP.
Patients and Methods
From January 2008 through November 2012, 4 023 patients
underwent RARP by a single surgeon at our institution.
Retrospective analysis of prospectively collected data
identified 3 362 men who had minimum of 1-year follow-up.
This cohort of patients was stratified into six groups: Group I,
aged ≥70 years (451 patients); Group II, BMI ≥35 kg/m
2
(197); Group III, prior bladder neck procedures (103); Group
IV, prostate weight ≥80 g (280); and Group V, salvage
prostatectomy (41). Group VI consisted of patients (2 447)
with none of these risk factors. Continence outcomes at
follow-up were analysed for all groups.
Results
The continence rate at 1 year and mean (SD) time to
continence in different groups were: for patients aged
≥70 years, 85.6% and 3.2 (4.5) months; BMI of ≥35 kg/m
2
,
87.8% and 3.1 (4.5) months; prior bladder neck treatment,
82.4% and 3.4 (4.7) months; prostate weight of ≥80 g, 85.8%
and 3.3 (4.4) months; salvage procedures, 51.3% and
6.6 (8.3) months; and in Group VI (none of the risk factors),
95.1% and 2.4 (3.2) months. The continence rate was
significantly higher in group VI compared with the salvage
group (group V) at the different follow-up intervals
(P < 0.001). When compared with the other groups (I–IV),
the continence rate, although higher, was not statistically
significant at the different intervals in group VI (no risk). The
mean time to continence was significantly lower in group VI
compared with the other groups (I–V; P < 0.001).
Conclusions
This study has shown that selected risk factors adversely
affect the time to return of continence after RARP, yet aside
from salvage patients, there was no statistically significant
difference demonstrated between the adverse-risk groups
included. Patients undergoing salvage RP had significantly
lower continence rates at the various intervals compared with
the other groups. Patients with the risk factors identified
should be counselled concerning expectations for achieving
urinary continence.
Keywords
prostatectomy, robot-assisted radical prostatectomy,
predictors, urinary incontinence
Introduction
With the use of PSA screening and increasing public
awareness about prostate cancer, younger and healthier men
are being diagnosed with localised prostate cancer [1–3].
According to the American Cancer Society, 233 000 new
cases of prostate cancer will be diagnosed [3]. With this rise
in cases, radical prostatectomy (RP), a standard of care for
localised prostate cancer, has evolved from open through
laparoscopic to robot-assisted RP (RARP) in the last decade
[4–7].
In 2014, 80% of RPs were performed using a robotic platform
in the USA [8]. The 10–15-year cancer-specific survival for
these patients after RP has been reported as 90–95%. With
younger patients being diagnosed and living longer, there is an
© 2015 The Authors
BJU Int 2015; 116: 764–770 BJU International © 2015 BJU International | doi:10.1111/bju.13106
wileyonlinelibrary.com Published by John Wiley & Sons Ltd. www.bjui.org
Robotics and Laparoscopy