UK Renal Registry 14th Annual Report: Chapter 11 Clinical, Haematological and Biochemical Parameters in Patients receiving Renal Replacement Therapy in Paediatric Centres in the UK in 2010: National and Centre-Specific Analyses Rishi Pruthi a , Heather Maxwell b , Anna Casula a , Yincent Tse c , Manish D Sinha d , Catherine O’Brien e , Malcolm Lewis f , Carol Inward g a UK Renal Registry, Bristol, UK; b Royal Hospital for Sick Children (Yorkhill), Glasgow, UK; c Royal Victoria Infirmary, Newcastle, UK; d Evelina Childrens Hospital, London, UK; e Birmingham Children’s Hospital, Birmingham, UK; f Manchester Children’s Hospital, Manchester, UK; g Bristol Royal Hospital for Children, Bristol, UK Key Words Biochemical variables : Children : Dialysis : ERF : Haemo- globin : Height : Quality improvement : Transplant : Weight Abstract Background: The British Association for Paediatric Nephrol- ogy Registry was established to analyse data related to renal replacement therapy (RRT) for children. The registry receives data from the 13 paediatric nephrology centres in the UK. Aim: To provide centre specific data so that individual centres can reflect on the contribution that their data makes to the national picture and to determine the extent to which their patient parameters meet nationally agreed audit standards for the management of children with established renal failure. Method: Data returns have been a mixture of electronic and paper returns. Data were analysed to calculate summary statistics and where applicable the percentage achieving an audit standard. The standards used were those set out by the Renal Association and the National Institute for Health and Clinical Excellence. Results: Anthropometric data confirmed that children receiving RRT are short compared to healthy peers. Amongst patients with a height z-score of <2 SD between 2000 and 2010, 27% were receiving growth hormone if they were on dialysis compared to 10% if they had a functioning transplant. Blood pressure was higher in children receiving RRT than in healthy children with wide inter-centre variation. The percentage of patients achieving the treatment standards for haemoglobin and ferritin has gradually increased over the last decade, more noticeably in dialysis patients. Analysis by age showed that the pro- portion of children with a haemoglobin below the standard was greatest for the under 5 years age group irrespective of RRT modality. The control of renal bone disease remained challenging. Conclusions: Optimizing growth in children on RRT remains challenging and the control of bone biochemistry in children on dialysis is imperfect. However there is some room for optimism as this year’s data shows an improving trend in the control of anaemia and systolic blood pressure. Nephron Clin Pract 2012;120(suppl 1):c219–c232 Published online: September 1, 2012 Fax +41 61 306 12 34 E-Mail karger@karger.ch www.karger.com # 2011 S. Karger AG, Basel 1160–2110/12/1205–0219$38.00/0 Accessible online at: www.karger.com/nec Carol Inward UK Renal Registry, Southmead Hospital, Southmead Road, Bristol, BS10 5NB, UK Email: renalregistry@renalregistry.nhs.uk DOI: 10.1159/000342855 Downloaded by: 3.239.7.17 - 12/19/2021 10:57:58 AM