Original Article Egyptian Journal of Health Care, 2023 EJHC Vol. 14. No.2 627 Effect of Mother Voice on Physiological Parameters and Level of Consciousness of Patients in Pediatric Intensive Care Unit Asmaa Attia Tolba* 1 , Fatmaa Elzahraa Kamal Elsayed 2 , Amira Hassan Abdelfatah 3 , Safaa Mahmoud Ahmed 4 , Azza Ahmed Eltayeb 5 , Sanaa Saber Mohamed 6 . 1. Lecturer of Critical Care & Emergency Nursing, Faculty of Nursing, Assuit University, Egypt. 2. Lecturer of Pediatric Nursing, Faculty of Nursing, Sohag University, Egypt. 3. Lecturer of Pediatric Nursing, Faculty of Nursing, Assuit University, Egypt. 4. Fellow of critical care nursing and emergency, Assiut University Hospitals, Egypt. 5. Professor and head of PICU Children university Hospital, Assiut University , Egypt 6. Lecturer of Critical Care & Emergency Nursing, Faculty of Nursing, Sohag University, Egypt. * Corresponding Author: asmaa_atiaa2010@aun.edu.eg. Abstract Reduction in sensory inputs is considered one of the most common complications following intensive care unit (ICU) admission. Changes in physiologic parameters are brought about by auditory stimulation, which hastens recovery. So, this study aimed to examine the effect of mother voice on physiological parameters and level of consciousness of patients in pediatric intensive care unit. Research design and setting: A quiz experimental study was carried out from beginning of March 2022 till end of October 2022 in pediatric ICU at Assiut University Children’s Hospital, Egypt. Sample: A purposive sample of 60 patients was assigned into two equal groups: control and intervention groups. Study tools: Two tools were utilized to collect data: physiological parameters assessment sheet, and Glasgow Coma Scale. Results: The mother's voice had a statistically significant effect on oxygen saturation and level of consciousness in the intervention group compared to the control group at the 3 rd day with (p.value < 0.05). While there was no statistical significant difference among the study groups as regard heart rate, systolic and diastolic blood pressure from the 1 st to the 3 rd day. Conclusion: Auditory stimulation utilizing the mother's voice has a significant effect on improving the level of consciousness and oxygen saturation in comatose pediatric patients. Recommendations: Replication of other studies utilizing multimodal stimulation (auditory, visual, and tactile stimulation) can be used either independently or in combination to examine its effect on several additional factors such as mechanical ventilation and length of stay. Keywords: Mother Voice, Physiological Parameters, Level of Consciousness, Pediatric Intensive Care Unit. Introduction: Loud noises, bright lights, and a reduction in stimulation create a very stressful environment for patients in the intensive care unit (ICU) (Anusha, and Radhika, 2022). In the ICU, there are four different types of stress: physical, mental, communicative, or environmental, according to a study by (Krampe et al., 2021). The last type, the environment, is unaffected by these factors, whereas the first three types are determined by the patient, the diagnosis, and the course of treatment. Particularly, exposure to multiple stimuli in the ICU, such as sounds, lights, and temperatures, has a negative effect on critically ill patients (Gultekin et al., 2018; Krampe et al., 2021). On the one hand, the sound of alarms and nearby activity may overwhelm critically ill patients (Tronstad et al., 2021). The hospital's environmental and architectural factors have a significant impact on patients’ sensory environment and whether they are at risk of receiving too much or too little stimulation (Tronstad et al., 2021; Verderber et al., 2021). The risk of sensory overload or deprivation is further increased by other patient treatment considerations, such as intubation, because the patient is unable to express their needs (Krampe et al., 2021). Critical care nurses and other