298 Care: Jurnal Ilmiah Ilmu Kesehatan Vol .9, No. 2, 2021, hal 298-308 Tersedia online di https://jurnal.unitri.ac.id/index.php/care ISSN 2527-8487 (online) ISSN 2089-4503 (cetak) Cara Mengutip: Triardhana, Y.A., Sari, G.M., & Liben, P. (2021). Aktivitas Fisik Akut Interval dan Kontinyu Intensitas Moderat Tidak Dapat Menurunkan Kadar Biomarker Resorpsi Tulang CTx. Care:Jurnal Ilmiah Ilmu Kesehatan, 9(2), 298-308 Retrieved from https://jurnal.unitri.ac.id/index.php/care/article/view/1510 AKTIVITAS FISIK AKUT INTERVAL DAN KONTINYU INTENSITAS MODERAT TIDAK DAPAT MENURUNKAN KADAR BIOMARKER RESORPSI TULANG CTx Yanuar Alfan Triardhana 1* , Gadis Meinar Sari 2 , dan Paulus Liben 3 1,2 Program Magister (S2) Ilmu Kesehatan Olahraga Fakultas Kedokteran Universitas Airlangga Jl. Mayjen. Prof. Dr. Moestopo 47, Surabaya 60132 3 Departemen Rehabilitasi Medik Pascasarjana Universitas Airlangga Jl. Mayjen. Prof. Dr. Moestopo No. 6 - 8 *Corresponding Author : yanuar.alfan.triardhana-2017@fk.unair.ac.id ABSTRACT Physical activity will affect the bone remodeling process and have an impact on bone health. Physical activity would activate osteoblasts and precursor through lane HPA Axis to start the process of bone remodeling. When the process of remodeling of bone occurs there are molecules of collagen which is released into the circulation, i.e. CTx (osteoclast marker). The aim of this study to showing effect of acute continuous and interval physical activity with moderate intensity on CTx. This research was using the type of research field experimental by using the pretest-posttest design. Sixteen adult male was selected on this study and devided into 2 with 8 people every group. Blood sample was taken before and 1 hour after the physical activity. The results obtained showed the acute effect of continuous physical activity with moderate intensity to CTx with a mean pretest 0,93 ± 0,566 > posttest 0,559 ± 0,398 ng/mL (p = 0.173 > 0.05), acute effect of moderate intensity interval physical activity on CTx with the mean pretest 0,451 ± 0,302 < posttest 0,524 ± 0,284 ng/mL (p = 0.693 > 0.05). From this study can be concluded that there was no effect of acute continuous and interval physical activity with moderate intensity on CTx. Keywords: continuous physical activity, bone remodelling, CTx, interval physical activity,. ABSTRAK Aktivitas fisik akan mempengaruhi proses remodelling tulang dan berdampak pada kesehatan tulang. Aktivitas fisik akan mengaktifkan osteoblas dan prekusornya melalui jalur HPA Axis untuk memulai proses remodelling tulang. Saat proses remodelling tulang terjadi terdapat molekul kolagen yang dilepaskan ke sirkulasi, yaitu CTx (marker osteoklas). Penelitian ini bertujuan untuk mengetahui pengaruh aktivitas fisik akut kontinyu dan interval intensitas moderat terhadapt CTx. Penelitian ini menggunakan jenis penelitian eksperimantal lapangan dengan menggunakan rancangan penelitian the pretest-posttest design. Enam belas laki-laki dewasa dipilih dalam penelitian ini, dan dibagi kedalam 2 kelompok dengan jumlah masing-masing 8. Pengambilan sampel darah dilakukan sebelum dan 1 jam setelah aktivitas fisik. Hasil yang didapat yaitu aktivitas fisik akut kontinyu intensitas moderat terhadap CTx dengan rerata pretest 0,93 ± 0,566 > posttest 0,559 ± 0,398 ng/mL (p = 0,173 > 0,05), aktivitas fisik akut interval intensitas moderat terhadap CTx dengan rerata pretest 0,451 ± 0,302 < posttest 0,524 ± 0,284 ng/mL (p = 0,693 > 0,05). Dapat brought to you by CORE View metadata, citation and similar papers at core.ac.uk provided by Jurnal Universitas Tribhwuana Tunggadewi