www.clinical.proteomics-journal.com Page 1 Proteomics - Clinical Applications Received: 06 30, 2017; Revised: 01 03, 2018; Accepted: 01 17, 2018 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/prca.201700084. This article is protected by copyright. All rights reserved. An MRM-based cytokeratin marker assay as a tool for cancer studies: application to lung-cancer pleural effusions Anna Perzanowska 1 , Agnieszka Fatalska 1 , Grzegorz Wojtas 2 , Andrzej Lewandowicz 3 , Agata Michalak 2 , Grzegorz Krasowski 2 , Christoph H. Borchers 4-7 , Michal Dadlez 1 , Dominik Domanski 1 1 Mass Spectrometry Laboratory, Institute of Biochemistry and Biophysics - Polish Academy of Sciences, Warsaw, Poland 2 Mazovian Center of Pulmonary Disease and Tuberculosis Treatment, Otwock, Poland 3 Department of Geriatrics, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland 4 Proteomics Centre, Segal Cancer Centre, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada 5 Gerald Bronfman Department of Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada 6 University of Victoria - Genome British Columbia Proteomics Centre, University of Victoria, Victoria, British Columbia, Canada 7 Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada