100 Citation: Sager O, Beyzadeoglu M, Dincoglan F, Demiral S, Uysal B, et al. (2020) Obsessive compulsive disorder (ocd) as a severe mental health disorder: A concise review of management with radiosurgery for intractable disease. J Surg Surgical Res 6(2): 100-105.DOI: https://dx.doi.org/10.17352/2455-2968.000106 https://dx.doi.org/10.17352/jssr DOI: 2455-2968 ISSN: CLINICAL GROUP Review Article Obsessive compulsive disorder (ocd) as a severe mental health disorder: A concise review of management with radiosurgery for intractable disease Omer Sager*, Murat Beyzadeoglu, Ferrat Dincoglan, Selcuk Demiral, Bora Uysal, Hakan Gamsiz, Fatih Ozcan, Onurhan Colak and Bahar Dirican Department of Radiation Oncology; University of Health Sciences, Gulhane Medical Faculty, Ankara, Turkey Received: 09 June, 2020 Accepted: 30 June, 2020 Published: 01 July, 2020 *Corresponding author: Dr. Omer Sager, MD, Depart- ment of Radiation Oncology; University of Health Sci- ences, Gulhane Medical Faculty, Gn.Tevfik Saglam Cad. 06018, Etlik, Kecioren, Ankara, Turkey, Tel: + 90505 0769465; 90312 3044683; Fax: +90 312 304 4680; E- mail: Keywords: Obsessive compulsive disorder; Radiosur- gery; Gamma Knife Radiosurgery (GKRS) https://www.peertechz.com Introduction Obsessive Compulsive Disorder (OCD) is among the most important psychiatric disorders significantly deteriorating the mental health of affected patients along with severe consequences such as unemployment, marriage failure, and maladjustment in familial relationships. Patients suffer from substantial impairment in their quality of life. Available first-line therapeutic strategies including exposure and response prevention, cognitive-bahavioural-therapy, and pharmacological agents such as selective serotonin reuptake inhibitors and tricyclic antidepressants may result in clinical improvement in majority of patients, however, approximately 20% of patients have refractory OCD unresponsive to first-line management, and a subgroup of patients unresponsive to first- line therapies suffer from severe debilitating symptoms referred to as intractable OCD. No consensus exists for management of patients with intractable OCD and treatment decisions Abstract Obsessive Compulsive Disorder (OCD) is a mental health disorder with characteristic features including uncontrollable, reoccurring thoughts referred to as obsessions, and excessive urges to perform repeated certain routines referred to as compulsions. Affected patients may suffer from tics, anxiety, negative social behaviours and self mutilation. Symptoms of patients may be intrusive, anxiety-provoking, and rather distressing which may significantly compromise both social and occupational functioning. Deterioration in quality of life may occur as a consequence of unemployment, marriage failure, and maladjustment in familial relationships. Initial management of OCD may include exposure and response prevention, cognitive-bahavioural-therapy, and pharmacological agents such as selective serotonin reuptake inhibitors and tricyclic antidepressants. These management strategies may be effective for the majority of patients suffering from OCD. However, approximately 20% of patients have refractory OCD unresponsive to first-line therapies and a subgroup of patients unresponsive to first-line therapies suffer from severe debilitating symptoms referred to as intractable OCD. Radiosurgery has a long history as an excellent radiotherapeutic modality for management of several intracranial disorders. Radiosurgical or gamma capsulotomy technique involving discrete, circumscribed lesions in white matter of the anterior limb of the internal capsule has been introduced by the Swedish neurosurgeon Lars Leksell. Gammaknife Radiosurgery (GKRS) system has been used as a viable alternative to open surgical anterior capsulotomy procedures and gained popularity and widespread acceptance with accumulating evidence from several centers worldwide. Herein, we provide a concise review including the definition, epidemiology and symptomotology of OCD, patient selection criteria, and management options with focus on radiosurgery.