Assessment of Mental Stress Through the Analysis of Physiological Signals Acquired From Wearable Devices Matteo Zanetti, Luca Faes, Mariolino De Cecco, Alberto Fornaser, Martina Valente, Giovanni Guandalini and Giandomenico Nollo Abstract Mental stress is a physiological state that directly correlates to the quality of life of individuals. Generally speaking, but especially true for disabled or elderly subjects, the assessment of such condition represents a very strong indicator corre- lated to the difficulties, and, in some case, to the frustration that derives from the execution of a task that results troublesome to be accomplished. This article describes a novel procedure for the assessment of the mental stress level through the use of low invasive wireless wearable devices. The information contained in electrocardiogram, respiratory signal, blood volume pulse, and electroencephalogram was extracted to set up an estimator for the cognitive workload level. A random forest classifier was implemented to assess the level of mental stress starting from a pool of 3481 features computed from the aforementioned physiological quantities. The proposed system was applied in a scenario in which two different mental states were elicited in the subject under investigation: first, a baseline resting condition was induced by the presentation of a relaxing video; then a stressful cognitive state was provoked by the M. Zanetti (B ) · M. De Cecco · A. Fornaser · G. Nollo Department of Industrial Engineering, University of Trento, via Sommarive, 9, 38123 Povo, TN, Italy e-mail: matteo.zanetti@unitn.it M. De Cecco e-mail: mariolino.dececco@unitn.it G. Nollo e-mail: giandomenico.nollo@unitn.it L. Faes Department of Energy, Information Engineering and Mathematical Models, University of Palermo, Viale delle Scienze, Ed. 9, 90128 Palermo, PA, Italy M. Valente Center for Neuroscience and Cognitive System, University of Trento, Corso Bettini, 31, 38068 Rovereto, TN, Italy G. Guandalini Villa Rosa hospital, Azienda Provinciale per i Servizi Sanitari (APSS), via Spolverine, 84, 38057 Pergine Valsugana, TN, Italy © Springer Nature Switzerland AG 2019 A. Leone et al. (eds.), Ambient Assisted Living, Lecture Notes in Electrical Engineering 544, https://doi.org/10.1007/978-3-030-05921-7_20 243