Int. J. Agr. Ext. 09 (03) 2021. 477-483 DOI: 10.33687/ijae.009.03.3734 477 Available Online at EScience Press International Journal of Agricultural Extension ISSN: 2311-6110 (Online), 2311-8547 (Print) https://esciencepress.net/journals/IJAE EFFECT OF CLODINAFOP-PROPARGYL COMPOUND AGAINST LAND SNAIL, HELIX ASPERSA: IMPLICATIONS FOR CONTROL Soha A. Mobarak*, Nema M. El-Abd, Randa A. Kandil Agriculture Harmful Animals Research Department, Plant Protection Research Institute, ARC. Dokki, Giza. Ministry of Agriculture and Land Reclamation, Egypt. ARTICLE INFO ABSTRACT Article History Received: June 20, 2021 Revised: September 02, 2021 Accepted: September 28, 2021 The effect of clodinafop –propargyl against the mucus of land snail, Helix aspersa, was studied under laboratory and field conditions during autumn 2020 season. Snails were exposed to serial concentrations of the clodinafop-propargyl for successive seven days using contact and bait techniques. The Median Lethal concentration (LC50) was determined and the effect of LC25 of test compound was examined on the total protein and alkaline phosphatase after seven days of treatment. In the field, the effect of the test compound used poison bait was evaluated after 21 days against H. aspersa on mango nursery trees at a reclaimed land in Abu- Rwash, Giza Governorate, Egypt. The effect of clodinafop –propargyl (25.200 ppm) was compared with methomyl (4.000 ppm) a compound recommended by Ministry of Agriculture and Land Reclamation in the field trials. The effects were evaluated after 1, 3,7, 15, and 21 days of treatment with both compounds. Based on the laboratory data for clodinafop –propargyl the LC50 were 6.750 ppm for the contact and 8.250 ppm for the bait method after seven days of treatment. Moreover, the compound caused a reduction in the total protein and alkaline phosphatase compared with the control. In the field, the compound caused 90.7% reduction in snail population compared to 75.0% reduction caused by methomyl after 21 days of treatment. Therefore, it be concluded that clodinafop – propargyl compound can be used as poison bait in the control programs to combat land snails. Keywords Helix aspersa Pest control Clodinafop propargyl Alkaline phosphatase Total protein Corresponding Author: Soha A. Mobarak Email: soha_snailes@yahoo.com © The Author(s) 2021. INTRODUCTION Land gastropods comprise a highly diverse group of molluscs. Several species of terrestrial snails and slugs spread into new areas outside their original habitat range due to agricultural and human activities. These species become pests in these new areas by causing damage to major economical field crops and horticulture plants. Moreover, they transmit the parasitic diseases that affect humans and farm animals (Pokryszko, 2002). The brown garden snail, Helix aspersa, is a terrestrial land snail, and one of the known pest species in the world. It is widespread in several countries living under different environmental conditions as a pest of field, ornamental, and horticulture crops (Rosenberg G. and Bouchet., 2014; Eshra, 2013). The present study was conducted to reduce the secretion of mucous (the first lines of defence) by using clodinafop- propargyl. Davies and Hawkins (1998) mentioned that the mucous, in general, is used to protect cell surfaces exposed to the external environment and is