International Journal of Science and Healthcare Research Vol.4; Issue: 1; Jan.-March 2019 Website: www.ijshr.com Original Research Article ISSN: 2455-7587 International Journal of Science and Healthcare Research (www.ijshr.com) 268 Vol.4; Issue: 1; January-March 2019 Analysis of the Effect of Development of Hospital Management Information System Based on Knowledge Management on Employee Performance of Dr Wahidin Sudirohusodo, Makassar Dewi Rizki Nurmala 1 , Wibowo 2 , Noer Bahry Noor 3 , Indrianty Sudirman 3 1 Administration Section of RSUP Dr. Wahidin Sudirohusodo 2 Center for Research and Development of Health Services Resources Health Research and Development Agency of the Indonesian Ministry of Health, Jakarta. 3 Postgraduate Program in Public Health, Hasanuddin University, Makassar Corresponding Author: Dewi Rizki Nurmala ABSTRACT This study aims to (1) find out the relationship between knowledge management hospital management information system development on employee performance, (2) analyze the influence of knowledge management hospital management information system development on employee performance, (3) analyze the partial influence of home management information system development knowledge management based pain towards employee performance. The study uses quantitative methods with explanatory correlational designs. Sampling is done by purposive sampling method with a sample size of 94 people. Data were analyzed using Yates Correction Test and Multiple Regression. The results of the study show that there is a relationship between the development of knowledge management SIMRS and employee performance. There is the influence of the development of knowledge management SIMRS on employee performance. Only 2 of the 4 knowledge management SIMRS development variables have a partial effect on employee performance, namely Knowledge Transfer and Knowledge Application. Keywords: Knowledge Management Process, SIMRS, Employee Performance INTRODUCTION Today the development of organizations in all sectors is increasingly leading to intense competition, competition in the form of services, ease of systems and product excellence continues to force every organization to make improvements and improvements. Knowledge is considered to be an important weapon in achieving and maintaining an organization's competitive advantage (Rastogi 2000; Senge 2000). Knowledge has a very important role in the progress of a company / organization. Many companies increasingly recognize the importance of knowledge as one of the capital to achieve competitive advantage. The more advanced knowledge the company has, the higher the company's competitiveness. Knowledge creation in an organization cannot be done instantly, but it requires processes and enabler factors (supporting factors to make it happen). The stages of creating knowledge in organizations in the context of the application of knowledge management begin with enablers factors that will trigger a knowledge management process, which then results in organizational creativity, which in turn will have an impact on organizational performance (Lee & Choi, 2003). Available electronic resources are the first target for information seekers, faced with new challenges to provide relevant and timely information and come from many sources. In other words it is challenged to provide the entire spectrum of information, not only limited to explicit knowledge, so it is necessary to explore the concept of applying Knowledge Management in the work environment, including hospitals which are a very important part of a health system.