Research Article This work is licensed under a CC BY 4.0 License International Research Journal of Ayurveda & Yoga Vol. 5 (4),01-08, April, 2022 ISSN: 2581-785X; https://irjay.com/ DOI: https://doi.org/10.47223/IRJAY.2022.5401 Clinical Study of Brihatsindooradya Taila and its Malahar on Kustha w.s.r. to Chronic Plaque Psoriasis Sumitra 1 , Sanjay Kumar 2 , Kshipra Rajoria 3 , Vijay Shankar Verma 4 1. Medical Officer, Shri Mohata Ayurvedic Rasayanshala, Bikaner (Raj.) 2. Associate . Professor , Dept. Of RasShastra and Bhasijya Kalpna , National institute of Ayurveda Deemed to Be University , Jaipur (Raj. ) 3. Lecturer, Dept. Of Panchkarma , National institute of Ayurveda Deemed to Be University , Jaipur (Raj. ) 4. BAMS MD( Ayu), Jaipur (Raj.) INTRODUCTION The skin is the first organ of the body to come into contact with environmental factors like physical, chemical, and biological pollutants. Changes in external stimuli and the body's inherent ability to deal with these elements create spontaneous remissions and relapses. The skin serves as a Article Info Article history: Received on: 18-03-2022 Accepted on: 21-04-2022 Available online: 30-04-2022 Corresponding author- Sumitra, Medical Officer, Shri Mohata Ayurvedic Rasayanshala, Bikaner (Raj.) Email id:-dr.sumitra.bkn@gmail.com ABSTRACT: Background: In Ayurveda, skin ailments are categorized as "kustha." In skin diseases, external use of drugs is just as important as internal therapy because it may provide greater and faster symptom relief. Acharya Sushrut while prescribing the treatment for kustha according to dhatugatawa, mentioned shodhan and alepana as first choice of management for twakgata kustha hence lepana karma has been considered as an ideal therapeutic measure for these diseases. Aim: The aim was to evaluate the role of Ayurveda treatment modalities in Kushtha. To conduct the pharmaceutical – analytical study on BST and its malahar .To study the comparative efficacy of Brihatsindoordya Taila (BST) and its malahar in the management of kustha w.s.r.to chronic plaque psoriasis. Materials and Methods: The study was prospective, interventional with Randomized, Open labelled, Controlled trial and conducted in 30 clinically diagnosed patients with classical sign and symptoms of kushtha .The study was conducted on 30 clinically diagnosed patients of Kushtha divided into 2 groups having 15 patients in each group. Total 30 patients of kustha w.s.r. to chronic plaque psoriasis had been randomly divided into two groups was given Brihatsindoordya Taila (BST) & Brihatsindoordya Taila Malahar ( BSM ) for topical administration, twice a day, for a duration of 30 days respectively. Results: The observations and results concluded that drug i.e BST & BSM showed effective and highly significant results in signs and symptoms of Kushtha i.e (p<0.0001). Conclusion: This case study revealed the efficacy of Ayurveda therapy, including external, for 1 month in the management of Kushtha. Keywords: Chronic plaque psoriasis, Eka-Kushtha, Shamana, Shodhana. The study reveals that combination of Ayurvedic modalities gives significant result in lakshnas (Symptoms) like Aswedana, Mahavastu, MastyaShakalopama. Keywords: Kushtharoga, Maha Kushtha, Tri Dosha, Dhatugatawa, twakgata kustha, lakshnas, Aswedana, Mahavastu, MastyaShakalopama.