1 Pol Ann Med. [in Press] Research paper Michał Chlebiej 1 , Andrzej Rutkowski 1 , Anna Żurada 2 , Jerzy Gielecki 3 , Katarzyna Polak-Boroń 3 1 Faculty of Mathematics and Computer Science, Nicolaus Copernicus University in Toruń, Poland 2 Department of Radiology, Collegium Medicum, School of Medicine, University of Warmia and Mazury, Olsztyn, Poland 3 Department of Anatomy, Collegium Medicum, School of Medicine, University of Warmia and Mazury, Olsztyn, Poland Corresponding author: Katarzyna Polak-Boroń, Jagiellońska 52/11, 10-283 Olsztyn, Poland. Tel.:+48 889261947. E-mail address: Katarzyna.polakanat@gmail.com Interactive CT/MRI 3D Fusion for cerebral system analysis and as a preoperative surgical strategy and educational tool article info Article history Received 2 November 2021 Accepted: 29 November 2021 Available online: 20 December 2021 Keywords Virtual reality Augmented reality Magnetic resonance imaging (MRI) Computed tomography (CT) Cerebral vessels segmentation 3D image fusion Doi https://doi.org/ User license This work is licensed under a Creative Commons Attribution – NonCommercial – NoDerivatives 4.0 International License. AbstrAct I n t r o d u c t i o n : The development of systems that merge existing technologies with gathered data may bring some spectacular effects that are usable both in preoperative and educational processes. Augmented reality (AR) is one of the key aspects of the new medical approach. Newly fused data sets draw from it and give users a better overall experience. A i m : The main goal of this study was to enable the interactive presentation of patients’ CT and MRI combined data with the incorporation of AR tools consi- dering the accuracy of the data with an emphasis on vascular structures. M a t e r i a l a n d m e t h o d s : The registration method, reconstruction of the va- scular system using tubular structures, and error analysis using surface distan- ce measurements results were used in the system to provide accurate combined information about bony structures from CT volume and vascular objects and cerebral vessels from MRI. Results and discussion: The strategies concern a series of CTI volumes that could be used to analyze bony surgical procedures. The methods are prefer- red, especially to the most complicated and individually modifed bony struc- tures of the skull. Removing, replacing, or modifying these bony structures or elements of the skull could be used as an analysis of operating procedures at the particular stages of the operation during neurosurgical or otolaryngological techniques. C o n c l u s i o n s : Presented study regarded to an innovative system consisting of a CT and MRI datasets fusion. The distance analysis of the segmented vascular model and proposed method for stabilization of the human head combined with virtual sculpting technique. In conclusion, it was meaningful in many aspects of the scientifc-technological merge. Journal homepage: htps://www.paom.pl Polish Annals of Medicine