Author’s Accepted Manuscript Targeting human telomerase RNA component using antisense oligonucleotide induces rapid cell death and increases ATO-induced apoptosis in APL cells Leila Asghari-Kia, Davood Bashash, Ava Safaroghli-Azar, Majid Momeny, Mohsen Hamidpour, Seyed H. Ghaffari PII: S0014-2999(17)30371-0 DOI: http://dx.doi.org/10.1016/j.ejphar.2017.05.039 Reference: EJP71229 To appear in: European Journal of Pharmacology Received date: 14 March 2017 Revised date: 13 May 2017 Accepted date: 19 May 2017 Cite this article as: Leila Asghari-Kia, Davood Bashash, Ava Safaroghli-Azar, Majid Momeny, Mohsen Hamidpour and Seyed H. Ghaffari, Targeting human telomerase RNA component using antisense oligonucleotide induces rapid cel death and increases ATO-induced apoptosis in APL cells, European Journal o Pharmacology, http://dx.doi.org/10.1016/j.ejphar.2017.05.039 This is a PDF file of an unedited manuscript that has been accepted fo publication. As a service to our customers we are providing this early version o the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain www.elsevier.com/locate/ejphar