Eur. Radiol. 2, 330-334 (1992) © Springer-Verlag 1992
European
Radiology
Gastrointestinal radiology
Arterial and pseudoaneurysm ruptures complicating
liver transplantation
H. Caiilet 1 , P. Cauquil 1 , Y. Ajavon 1 , G. Rouhana 1 , J. P. Verdier 1 , D. Azoulay 2, H. Bismuth 2 , and J. P. Tessier ~
Departments of 1Radiodiagnosis, and 2Surgery Paul Brousse Hospital, 12-14 av. Paul Vaillant Couturier B. R 200. 94804, VillejuifCedex,
France
immunosuppressive therapy, liver transplantation has
become an accepted treatment for end-stage liver disease
and for few primary liver tumors in both children and
adults. The major complications of liver transplantation
are rejection, biliary tract and vascular complications. The
most common vascular complication is hepatic artery
thrombosis [1, 2]. The occurence of thrombosis usually
requires re transplantation because of severe graft failure,
delayed biliary leak or intermittent episodes of sepsis
[1-3]. Arterial ruptures (ARs) or pseudoaneurysm (PAs)
ruptures are uncommon but life - threatening complica-
tions following liver transplantation. The risk of a fatal
hemorrage requires prompt diagnosis and surgery. Gener-
ally these ruptures are a complication of infection [2] at
the site of vascular anatomosis. The PA may also be the re-
sult of arterial injury by a percutaneous biopsy or a biliary
drainage [4, 5]. In this study we report the clinical, radio-
logic and the findings evolution of seven acute vascular
hemorrages following liver transplantation.
Introduction
The first human liver transplantation was performed in
1963. Since 1980, because of the success of cyclosporine as
Correspondence to." H. Caillet
Methods
From 1983 through to December 1990, 640 liver trans-
plantations were performed in our institution. During this
period seven major arterial bleeding episodes occured
postoperatively. Three were caused by an HA rupture and
four by a PA rupture. Five of the seven patients died. All
were men (mean age 39 years). Patients had been trans-
planted for a variety of reasons. For four patients it was a
first transplantation, for two a second and for one a third.
The indications for re transplantation were rejection or a
new viral hepatitis on the graft. Including of previous
operations before transplantation, the patients had
undergone an average of 3,3 operations mean. In all cases
the transplantation was an orthotopic liver transplanta-
tion (OLT) and in all cases but one allograft re arterialisa-
tion was performed by end-to-end anastomosis between
the donor celiac axis and the recipient common hepatic ar-
tery. In the last liver, the re arterialisation was complex be-
cause of the multiple arterial supply of the graft. Before