This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/JPI.12643 This article is protected by copyright. All rights reserved PROFESSOR RUTH ESTELA ROSENSTEIN (Orcid ID : 0000-0002-8804-4395) DR DAMIAN DORFMAN (Orcid ID : 0000-0002-7967-9866) Article type : Original Manuscript MELATONIN PROTECTS THE RETINA FROM EXPERIMENTAL NON-EXUDATIVE AGE-RELATD MACULAR DEGENERATION IN MICE Hernán H. Diéguez 1 , María F. González Fleitas 1 , Marcos L. Aranda 1 , Juan S. Calanni 1 , María I. Keller Sarmiento 1 , Mónica S. Chianelli 1 , Agustina Alaimo 2 , Pablo H. Sande 1 , Horacio E. Romeo 3 , Ruth E. Rosenstein 1 , Damián Dorfman 1 Running title: Macular degeneration and melatonin 1. Laboratory of Retinal Neurochemistry and Experimental Ophthalmology, Department of Human Biochemistry, School of Medicine/CEFyBO, University of Buenos Aires/CONICET, Buenos Aires, Argentina. 2. Interdisciplinary Laboratory of Cellular Dynamics and Nanotools, Department of Biological Chemistry, School of Exact and Natural Sciences/IQUIBICEN, University of Buenos Aires/CONICET, Buenos Aires. 3. School of Engineering and Agrarian Sciences, Pontifical Catholic University of Argentina, BIOMED/UCA/CONICET, Buenos Aires, Argentina. Corresponding author: Dr. Damián Dorfman Departamento de Bioquímica Humana Facultad de Medicina/CEFyBO, UBA/CONICET, Accepted Article