M. Pérez-Moya, T. Kaisto, M. Navarro, L. J. del Valle, EUETIB-CEIB, Chemical Engineering Department, UPC. BARCELONATECH, C/Comte d’Urgell 187, 08036 Barcelona, Spain Faculty of Technology, Lahti University of Applied Sciences, Niemenkatu 73, 15101 Lahti, Finland Center for Research in Nano-Engineering (CrNE), and ETSEIB, Chemical Engineering Department, UPC. BARCELONATECH, Av Diagonal 647, 08028 Barcelona, Spain Degradation of bisphenol A (BPA, 0.5 L, 30 mg L ) was studied by photo- Fenton treatment, while Fenton reagents were variables. The efficiency of the degradation process was evaluated by the reduction of total organic carbon (TOC), the biochemical oxygen demand (BOD), and toxicity. For toxicity analysis, bacterial methods were found infeasible, but the in vitro assay of VERO cells culture was successfully applied. Experiments according to a 2 design of experiments (DOE) with star points and three center points for statistical validity allowed selecting those process conditions (Fe(II) and H O load) that maximized the process performance. Photo-Fenton process effectively eliminated BPA and partly degraded its by-products (residual TOC <15 %) under substoichiometric H O dose (100.62 mg L ) and at least 4 mg L Fe(II), after a 90-min treatment. All 1,* 2 1 3 1 2 3 −1 2 2 2 2 2 −1 −1 e.Proofing http://eproofing.springer.com/journals/printpage.php?token=0vjbU1y... 1 de 25 12/09/2016 22:55